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ATHENS, Greece, Sept. 18, 2023 /PRNewswire/ -- A novel study has shown that Senolytics, a new class of drugs, have the potential to prevent the transfer of senescence, a key mechanism of ageing, in recipients of older donor organs. The pioneering research, presented today at the European Society for Organ Transplantation (ESOT) Congress 2023, opens promising avenues for expanding the organ donor pool and enhancing patient outcomes. By transplanting older donor organs into younger recipients, researchers from Harvard Medical School and the Mayo Clinic investigated the role of transplantation in inducing senescence, a biological mechanism linked to ageing and age-related diseases. The researchers conducted age-disparate heart transplants from both young (3 months) and old (18–21 months) mice into younger recipients. Recipients of old hearts showed augmented frequencies of senescent cells in draining lymph nodes, livers, and muscles, in addition to augmented systemic mt-DNA levels, compared to recipients that received young grafts. Strikingly, transplanting old organs led to advanced physical and cognitive impairments in recipients. The research also uncovered a potential solution to this process by utilising Senolytics – a new class of drugs designed to target and eliminate senescent cells. When old donors were treated with Senolytics (Dasatinib and Quercetin) prior to organ procurement, the transfer of senescence was significantly reduced through a diminished accumulation of senescent cells and mt-DNA. Recipients who received old organs treated with Senolytics showed improved physical fitness that was comparable to observations in recipients of young organs. Maximillian J. Roesel, presenting the study as part of the group at Brigham and Women's Hospital, Harvard Medical School, commented, "Donor age plays a crucial role in transplant success, with recipients of older organs facing worse outcomes. Nevertheless, the use of older donor organs is essential to tackle the global organ shortage, and this research illuminates fundamental challenges and potential solutions for utilising older organs." "Moving forward, we will further investigate the potential role of Senolytics in preventing the transfer of senescence in humans. This research is extremely exciting as it may help us improve outcomes and also make more organs available for transplantation," concluded Stefan G. Tullius, the lead author of the study. Note to editors: A reference to the ESOT Congress 2023 must be included in all coverage.
AUCKLAND, New Zealand, Sept. 18, 2023 /PRNewswire/ -- Data Domain, a pioneering data and analytics consultancy, is making its debut as a New Zealand-owned company with a distinctive edge. As a division of the global premiere testing consultancy TTC Global, Data Domain is poised to provide a unique offering in the data landscape. What sets Data Domain apart is the collaboration of data intelligence, and TTC Global's testing expertise, both of which are honed through years of industry experience. It enables the company to simplify the rapidly evolving data landscape, whilst applying quality assurance, to focus on the core principle of data: answering business questions to unlock insights and gain a competitive edge. "By leveraging our relationship with TTC Global, Data Domain is uniquely positioned to provide comprehensive data and analytics solutions to our clients," said Tanida Poffley, General Manager at Data Domain. "Our commitment to excellence, innovative foresight derived from years of experience, makes us a trusted partner for businesses seeking data-driven success, not only in New Zealand but worldwide." Data Domain champions the use of industry-leading technology to enable data-driven business objectives, while advocating for modular components tailored to each client's unique needs. The company's mission is multi-faceted. It aims to accelerate data insights through executable digital enablement and data transformation initiatives. Modern data platforms, coupled with Data Domain's expertise and knowledge of industry best practices, enable faster delivery of scalable data products. Its extensive experience enables Data Domain to guide customers to pragmatically strategise, and implement modern data practices such as DataOps, federated data architectures, and advanced analytics. About Data Domain: Data Domain is a data and analytics consultancy with deep industry expertise, backed by the resources of TTC Global, a proven leader in Testing and Quality Assurance. Its mission is to simplify the complex data landscape, enabling businesses to harness the power of their data for informed, competitive decision-making. With a commitment to innovation, efficiency, and personalised solutions, Data Domain is poised to transform the way organisations approach data in the digital age. To learn more, visit https://www.datadomain.co.nz About TTC Global: TTC is a leading global software assurance provider with a focus on helping organisations transform the way they deliver technology. We have capabilities across a wide range of delivery areas that enable our clients to increase the speed and quality of technology development while reducing risk and cost. TTC was founded in 2004 to be a testing partner that could take global learnings and best practices and deliver them in a locally appropriate way. Fast forward nineteen years, with offices in New Zealand, Australia, Asia, the Americas, and Europe and strong partnerships with some of the world's largest organisations, this is still TTC's purpose today. To learn more, visit us at: https://www.ttcglobal.com/ For media inquiries and executive interview requests, please contact Krizelle Lacson at Krizelle.lacson@ttcglobal.com or 021 208 5909.
CIMC Vehicles (Group) Co., Ltd. 中集車輛(集團)股份有限公司 (Stock Code: 1839.HK/301039.SZ) CIMC Vehicles Becomes the Top Semi-trailer Manufacturer in the World for 11 Consecutive Years Starting a Business for the Third Venture in High Spirit towards a Promising Future ([15] September 2023, Hong Kong) As the world’s leader in the sophisticated manufacturing of semi-trailers and specialty vehicles, CMIC Vehicles (Group) Co., Ltd. (“CIMC Vehicles” or the “Group”, Stock code: 301039.SZ/01839.HK) is pleased to announce that Global Trailer, the world's leading magazine for semi-trailers, has recently officially released the Top 50 Semi-trailer Manufacturers from Around the World Based on Production Output for the Period from 1 July 2022 to 30 June 2023. As the only Chinese enterprise on the list, CIMC Vehicles takes the lead with a production output of nearly 152,000 units. Since 2013, CIMC Vehicles has been the top semi-trailer manufacturer in the world for 11 consecutive years. At the beginning of the third venture, CIMC Vehicles has achieved remarkable performance. In the first half of 2023, the net profit attributable to shareholders of the Company reached RMB1.90 billion, representing a significant increase of 418.52% compared to the same period last year. This achievement marks a historic milestone and represents a breakthrough for the Group. As the world’s leader in sophisticated manufacturing of semi-trailers and specialty vehicles, a pioneer in high-quality development of road transport equipment in China, and an explorer and innovator in new energy specialty vehicles in China, CIMC Vehicles has seized the opportunity of high-quality development arising from starting the third venture to develop main businesses. Adopting a "dual-wheel" drive structure, the Group consolidated its fundamentals in “Intercontinental Operation” and pooled resources to promote all businesses under the “National Unified Market for Commercial Vehicle and Specialty Vehicles”. In the Chinese market, the Group will promote the efficient deployment of the “Star-chained Manufacturing Network”. Through the integration of production and manufacturing resources, it has achieved a leapfrog improvement in market share, sales, and profits. It has also become a benchmark for the supply-side reform of the domestic semi-trailer industry, a model of high-quality development and a paradigm of dual-wheel drive. The “Star-chained Manufacturing Network” will promote the changes in end-to-end business models in the domestic semi-trailer business, which focuses on three categories of semi-trailers and integrates the procurement (LTS), production (LTP), circulation (LTL), manufacturing (LoM) and distribution (sales channels) resources of seven domestic semi-trailer plants. It will also promote continuous cost reduction and steady improvement in price competitiveness, shorten the cycle of product delivery, enhance mass delivery capacity relying on modular inventory, launch integrated tractor and trailer products, and promote the sales of new vehicles. For the overseas market, due to the forward-looking strategic arrangements, CIMC Vehicles has constructed six overseas "Light Tower" Plants. These have greatly improved production efficiency and their development has created the potential for the Group’s explosive performance in overseas markets. In the first half of 2023, the Group’s North American Business maintained a growth trend. The North American Business recorded a revenue of RMB6.23 billion with a year-on-year increase of 34.67%, higher than expected. Additionally, the North American Business successfully delivered new energy refrigerated trailers to local customers, becoming an industry benchmark for new energy refrigerated trailers. In the European market, CIMC Vehicles operated “SDC” and “LAG” brands. SDC ranked first in the UK market. LAG, an over 70-year-old company, ranked among the best in the European tank trailer market, with its high commercial value, low fuel consumption, and low weight. In the first half of this year, leveraging on a stable global supply chain system and advantages of intercontinental operation, the revenue from European Business increased by 28.12% to RMB1.63 billion year-on-year, and the gross profit margin increased by 1.81 percentage points. In emerging markets, with the promotion of “Belt and Road” initiative and the full expansion of the “going global” strategy for China’s commercial vehicles, the semi-trailers in emerging markets have vast space for high growth. The Group followed the development trend of emerging markets and actively captured opportunities for high growth in emerging markets. CIMC Vehicles has developed its businesses in Southeast Asia, the Middle East, South Africa, Central America and other regions. It continues to tap into the incremental market demand and achieve rapid growth. For a long time, CIMC Vehicles has proactively pursued low-carbon and green manufacturing, establishing the Sophisticated Manufacturing System represented by the "Light Tower" Plants. The Group has promoted the upgrading and renewal of environmentally friendly equipment and production lines, gradually achieving cost reduction and efficiency increase. Through years of relentless efforts, the Group has set a new benchmark for green and environmentally friendly practices in the industry. Up to now, CIMC Vehicles has built 23 "Light Tower" Plants at home and abroad. Among these, four have been rated as “national-level green plants”. The Group has taken solid steps towards sustainable development. Over the past 20 years, CIMC Vehicles has made concerted efforts to start the first venture featuring “earth breaking” and for the second venture featuring “intercontinental operation” relying on audacious and innovative strategic design and planning as well as targeted deployment and effective execution. At present, as China faces a complex and severe international environment and the arduous task of carrying out domestic reform, the Group has always maintained its strategic focus, constructed a new development pattern, accelerated the innovation and exploration of new energy and promoted high-quality development, starting a business for the third venture in high spirit toward promising future. Since the launch of the third venture, the Group has intensified the in-depth exploration of the new energy sector, actively promoted the development and innovation of new energy and intelligent products and developed an innovative platform that supports new energy tractors and trailers and provides integrated solutions for the transformation of traditional tractors and trailers. Those who work will succeed, and those who walk will arrive at their destination. In the journey of the third venture, the Group will pool resources to promote all businesses and enter the new energy commercial vehicle industry with innovative technology and business models. Meanwhile, the Group will rely on innovation to drive endogenous growth and achieve a steady improvement in the operation quality of six major businesses or groups, promoting the high-quality development of the road transportation equipment industry. -Ends- About CIMC Vehicles (Group) Co., Ltd CIMC Vehicles (Group) Co., Ltd. (“CIMC Vehicles”, Stock code: 301039.SZ/01839.HK) is the world’s leader in the sophisticated manufacturing of semi-trailers and specialty vehicles, a pioneer in the high-quality development of road transport equipment in China, and an explorer and innovator in new energy specialty vehicles in China. According to the 2022 Global OEM Ranking List published by Global Trailer, CIMC Vehicles ranked first among semi-trailer manufacturers in the world, for the eleventh year in a row. CIMC Vehicles had six major businesses or groups, namely “Light Tower Pioneer Business”, “North American Business” and “European Business” engaged in the global semi-trailer market, “Champion Tanker Business Group” with a focus on sophisticated manufacturing of truck bodies for specialty vehicles and van truck bodies, “TB Business Group – Dump Truck Business” and “TB Business Group – Urban Distribution Van Truck Bodies Business”, covering four major markets in the world, more than 40 countries and regions, and had 23 “Light Tower” Plants at home and abroad. For enquiries, please contact LBS Communications Consulting Limited: Joanne Chan Tel: (852)3679 3671 Email: jchan@lbs-comm.com Jason Ho Tel: (852)3752 2675 Email: jho@lbs-comm.com Isaac Chan Tel: (852)3752 2673 Email: ichan@lbs-comm.com
The first battery product produced at Gotion Germany Battery GmbH has been officially launched Stephan Weil, Governor of Lower Saxony, and other Chinese and German dignitaries jointly witnessed the ceremony Simultaneously, Gotion signed contracts with many internationally renowned companies such as BASF China, ABB, Ebusco, and Ficosa GÖTTINGEN, Germany, Sept. 17, 2023 /PRNewswire/ -- On the morning of September 16, the first locally produced battery product was officially launched in Göttingen, a famous university town in central Germany. This is a milestone event for Gotion's first battery production and operation base in Europe. The ceremony was witnessed by Stephan Weil, Governor of Lower Saxony, and Cong Wu, Consul General of China in Hamburg. On the same day, Gotion also signed cooperation agreements with internationally renowned companies such as BASF, ABB, Ebusco, and Ficosa. At the event, participating guests collectively pressed the start button to formally launch the first automated battery pack production line at Gotion's German base. When an AGV (Automated Guided Vehicle) slowly transported the first battery pack from the testing area to the guests, everyone erupted in enthusiastic applause. "I'm very lucky, it's a very good moment in my life." Andreas, a worker at the Göttingen factory who just signed the first battery pack, shared his excitement with more than 200 colleagues. The official commissioning and operation of the battery pack production line demonstrate that Gotion has achieved localized production and supply in Europe. Gotion's batteries have officially embarked on the path of "Made in Germany". "Our Göttingen factory's production line is highly automated, with an overall automation level of nearly 70%, and close to 80% in the module assembly stage," said Ray Chen, Vice President of Gotion Global. Klaus Gohde, General Manager of the Göttingen plant, stressed that there is a high degree of consensus and consistency of action among the Göttingen team in promoting the transformation of the plant from ICE business to battery business in a "One Gotion" approach. In addition, Steven Cai, Gotion's CTO, also unveiled the company's strategic planning in Europe. As he introduced, the current production capacity plan for the Göttingen factory is 20GWh, which is expected to be completed in four phases. Once fully operational, it is estimated to generate an annual output value of EUR 2 billion. Peter Willemsen, COO of Gotion Global and managing director of the German entities, said that the spirit of cooperation between China and Europe was important in efforts to "make Europe green again". The first production line of Gotion's Göttingen factory was officially put into mass production today. At present, the factory has received a large number of orders from Europe. It is expected that it can supply products for European customers from October. By mid-2024, the actual production capacity may reach 5GWh. "The battery pack products from the factory include those for commercial vehicles, energy storage systems, and passenger vehicles. Additionally, the factory will serve as an R&D, logistics, and after-sales service center for Gotion's European production and operations base." The high demand for orders was evident in the signing ceremony. On September 16, Gotion High-tech signed cooperation agreements with five internationally renowned companies, covering various aspects such as battery materials, product development, and the supply of automotive and energy storage products. Specifically, Gotion will further collaborate with BASF China on battery material-related projects. Gotion and ABB from Switzerland will work together on battery product supply and technology R&D, to support ABB's new factories in Europe and the United States. Cooperation with Ebusco will focus on the development and production of energy storage battery systems and wind and solar energy storage projects. In addition, Gotion will cooperate with Ficosa and Idneo in intelligent mobile energy storage and charging vehicles, battery banking, battery recycling, BMS, and Big Data engineering. Li Zhen, Chairman of Gotion, delivered the opening speech: "The official launch of the first battery pack today stands as a testament to the hard work and ingenuity displayed by all the factory's employees.We look forward to collaborating with European enterprises to promote carbon emission reduction in the EU and foster the dynamic growth of both new energy vehicles and industries." Mr. Stephan Weil, Governor of Lower Saxony, expressed in his speech that engines were the most important parts of fuel vehicles in the past, but in the future, batteries will be the core components of electric vehicles. The Göttingen factory project has a distinct advantage as it allows Gotion to manufacture power battery products that cater to the broad market demand in Göttingen for decades to come.
BEIJING, Sept. 17, 2023 /PRNewswire/ -- The China-ASEAN Expo (CAEXPO) is set to make its 20th appearance from September 16 to 19, 2023 in Nanning, Guangxi, China. Themed "Work together for a Harmonious Home and a Shared Future", CAEXPO serves as an international economic and trade event jointly confirmed by the leaders of China and ASEAN. NaaS Technology Inc. (NASDAQ: NAAS), a leading EV charging service provider, is poised to make its premiere at the event, and are set to showcase their innovative products and energy digitalization solutions at the expo. NaaS brings a broad portofolio of charing equipment especially for charging scenarios in ASEAN region, including 7kW/11kW/22kW wall-mounted AC piles, 150kW all-in-one high-protection DC fast-charging piles, 180kW/240kW high-power DC fast-charging piles, and 30kW wall-mounted DC fast-charging piles, etc., which are suitable for multiple scenarios such as home use, public station operation, high-speed service areas, fleet charging, and various destinations. The automatic charging robot also attracts wide attention, which is wholly designed in-house to streamline the charging process for the future EV ecosystem. Simply placing a order on mobile App would allow vehicle owners to witness the charging robot to complete automatic searching, accurate docking, automatic insertion of the charging gun, drive away and return to replenish, etc., thus effectively enhance the charging experience processes. In the process of energy transition, the new energy industry stands as the frontier of globalization-a theme that resonates worldwide. Precedence Research's data highlights that as of 2022, the global renewable energy market size reached USD 103.095 billion and is expected to elevate further to approximately USD 1998.03 billion by 2030. Against this backdrop, ASEAN has also established ambitious goals for decarbonization and renewable energy development. The ASEAN Plan of Action for Energy Cooperation (APAEC) Phase 2 aims for a 23% share of renewable energy in the total primary energy supply (TPES) and a 35% share of renewable energy in the region's installed power capacity by 2025. The huge market potential has attracted heightened attention from an expanding array of global stakeholders, where NaaS seizes this opportunity well and makes prominent proceeds. As the first U.S. listed EV charging service company in China, NaaS provides one-stop EV charging solutions for charging station manufacturers, operators, OEMs and enterprises, supporting every stage of the station lifecycle. According to its latest financial report, number of orders transacted through NaaS' network reached 98.2 million in the first half of 2023, representing an increase of 110% YoY; and charging volume transacted through NaaS' network reached 2,251 GWh, representing an increase of 112% YoY. As of June 30, 2023, more than 652,000 chargers in over 62,000 charging stations were connected and accessible on NaaS' network. Recently, NaaS' subsidiary Nengcang Technology has secured a RMB204 million energy storage order through strategic cooperation agreements with several enterprises, dedicated to improving photovoltaic-storage-charging integrated solutions. NaaS has also teamed up with Fortune 500 companies like Hyundai, PICC, CR, etc., so as to expand a broader range of business scenarios and help build ecosystem in new energy industry. The partnerships will bring out collaboration in charging infrastructure construction as well as digital and intelligent application of new energy. With its developed practices of energy digitalization in China, NaaS has also delivered solid movements of its internationalization layout in ASEAN and broader scope. Previously, in June, NaaS announced it had entered into a definitive agreement to acquire 89.99% of the issued and outstanding shares of Sinopower HK. On August 22nd, NaaS unveiled plans to fully acquire the Sweden-born leading EV charging solutions provider Charge Amps for SEK 724 million (USD $66.4 million), a landmark deal positioning the company to make significant strides to the global energy market, and its finale goal to become a leading player in the global new energy asset operation and management services market in the long term. CONTACT: Sabrina Wang, wangxuedong@newlink.com
SINGAPORE, Sept. 17, 2023 /PRNewswire/ -- XT.COM, the world's first socially infused trading platform, is thrilled to announce the listing of YESGO on its platform in the Main zone and the YESGO/USDT trading pair will be open for trading from 2023-09-18 08:00 (UTC). Users can deposit YESGO for trading since 2023-09-17 08:00 (UTC) Withdrawals for YESGO will open at 2023-09-19 08:00 (UTC) About YESGO YESGO is an BEP-20 token deployed on the Binance Smart Chain as a governance token in the closed-loop of the Yesgo ecology with a 9.64 billion max token supply. YESGO will play an important role in the Yes ecology, such as transactions, transfers, circulation GAS fees, chain game NFT asset leasing, loan handling fees, interest settlement, and enjoyment of board dividend certificates. Through the entire business closed loop, the token value drives community consensus, allowing players not only to earn huge profits through games but also to establish a medium for value transfer. The YESGO tokenomic model includes various allocation ratios, such as total burned, game rewards, destruction mechanism, combustion mechanism, ecological incentives, financing amount, and technical rewards. YESGO holders can initiate proposals and votes to determine fee parameters, repurchase parameters and product functions, etc. YESGO can also be used to pledge data monitoring function on the chain and Binance Chain transaction anti-pinch function. YESGO tokens can be used to play mini-games and provide fee rate discounts. YESGO tokens can be used to play mini-games, provide fee rate discounts, and pledge data monitoring function on the chain and Binance Chain transaction anti-pinch function. YESGO holders can initiate proposals and votes to determine fee parameters, repurchase parameters and product functions, etc. YESGO tokens can also be used to play mini-games and provide fee rate discounts. Albin Warin, CEO of XT.COM, expressed his delight at the listing of YESGO token on XT.com, saying "We are thrilled to have YES token listed on XT.com. The Yesgo project is an exciting addition to the blockchain ecosystem as its China's first open platform that empowers web2.0 to transform into web3.0. We look forward to a successful partnership with Yesgo and their community." About the YESGO Ecosystem Yesgo is a Web3.0 APP that combines SocialFi+NFT. Through new technologies and innovative models, Yesgo breaks down the development barriers of traditional short videos, allowing everyone to gain benefits. Yesgo is the first blockchain-based "Sing-to-Earn" and "Share-To-Earn" models that allow users to upload works and protect copyrights through blockchain technology. Yesgo mainly provides users with the creation and dissemination of short videos. Different from traditional platforms such as TikTok and Youtube, the biggest highlight of Yesgo is that all participants can share revenue with the platform and can obtain platform mining rewards for creating and viewing videos. Under the incentive of revenue sharing, Yesgo will attract users from all over the world to participate in providing traffic for shopping malls, live broadcasts, social networking, transactions, etc. on the platform, and further promote the expansion of the ecology. Yesgo's short video platform focuses on high-quality content, adopting a combination of self-development, cooperation with traditional high-quality game developers, and existing successful games to integrate blockchain technology into traditional classic games, etc. Yesgo's games focus on high-quality content, adopting a combination of self-development, cooperation with traditional high-quality game developers, and existing successful games to "blockchain-ize" traditional classic games, etc. Yesgo supports many popular games such as RPG games and Happy Landlords. Yesgo has just recently launched its video marketing campaign on the Nasdaq billboard in Times Square, New York. The video playback is simulcasted for 10 hours on September 10th, a significant milestone for Yesgo, as it will help to increase awareness of the YESGO token and the Yesgo project. The Nasdaq billboard is a unique opportunity to boost their brand visibility and connect with a vast, diverse audience. Yesgo has an ambitious roadmap for the future. In Q3 2023, they plan to launch the world's top 20 XT exchanges, the first horse racing competitive chain game, and a joint promotion with 100+ KOLs in the coin circle. They also plan to be reported by six authoritative media in Europe and America. In the first quarter of 2024, Yesgo plans to launch the world's top 10 exchanges, the Texas Hold'em board game, a Southeast Asian short video platform, and a Metaverse SDK platform. They also plan to launch a blockchain + AI platform, a joint promotion with 300+ KOLs in the coin circle, and be jointly reported by 15+ authoritative media in Southeast Asia. In the third quarter of 2024, Yesgo plans to develop a decentralized wallet, launch yesgoDEX, and launch a sheep leisure chain game. They also plan to have a joint promotion with 300+ KOLs in the coin circle and be jointly promoted by 15+ authoritative media in the world. In the first quarter of 2025, Yesgo plans to launch Coinsafe Exchange, develop the yesgo ecological public chain, launch the Bloodbath Arena shooting game, and establish the yesgo gaming club to compete with global gaming players and build brand influence. They also plan to have a joint promotion with 50+ authoritative media around the world. Website: www.hiyesb.com Twitter: twitter.com/Yesgo_Web3 Telegram: t.me/+Hgh22mTEnoo3ZjE1 About XT.COM Founded in 2018, XT.COM serves more than 6 million registered users, over 500,000+ monthly active users, 40+ million users in the ecosystem, and more than 800 tokens with 1000+ trading pairs. Since then, XT.COM crypto exchange has expanded its offerings by covering a rich variety of trading categories to provide a secure, trusted, and intuitive trading experience for its large user base. One such addition is crypto futures trading which includes USDT-M Futures and coin-M futures perpetual contracts, as well as copy trading that allows users to replicate top traders in real time with just one click. Additionally, the Futures Grid allows users to automate the buying and selling of futures contracts to make profits. Website: www.xt.com Twitter: twitter.com/XTexchange Telegram: t.me/XTsupport_EN
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