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"Aiming to offer a Dengue antiviral treatment course in $100 price range" Hyundai Bioscience decides to conduct dengue clinical trials in Brazil, which has the largest number of Dengue patients and offers a fast-track approval SEOUL, South Korea, April 25, 2024 /PRNewswire/ -- Hyundai Bioscience announced on April 25th that, after multiple consultations with global clinical research organizations (CRO), it has decided to conduct clinical trials for its 'niclosamide-based Dengue antiviral' in Brazil, which has the highest number of dengue cases and deaths in the world. Hyundai Bioscience outlined two main reasons for choosing Brazil as its Dengue clinical trial regions: Firstly, Brazil has been the most affected country by the Dengue virus. According to the Brazilian health authorities, as of April 10th this year, there has been 3,062,181 reported cases of Dengue infections with 1,256 deaths. Brazilian health authorities expect the number of infections this year to more than double last year's 1.6 million cases. 71 cities in Southern Brazil, including São Paulo and Rio de Janeiro, have declared a public health emergency over Dengue. Secondly, Brazil offers a fast-track process for drugs targeting diseases with no available treatments. Although the number of Dengue cases and deaths is rapidly increasing not only in Brazil but globally, there is no antiviral treatment available. Niclosamide, the active pharmaceutical ingredient of Hyundai Bioscience's Dengue antiviral, has been known to have antiviral efficacy against all serotypes of Dengue viruses through previous in vitro studies, and its safety has also been confirmed through Hyundai Bioscience's preclinical and clinical studies for COVID-19. This may enable to skip preclinical study and to proceed promptly to clinical study through the fast-track approval process. Dengue treatment has not been developed for over 50 years since the Dengue virus was discovered. Development of Dengue treatments is challenging because it must be effective against all four serotypes of the Dengue virus as well as against their mutants. Hyundai Bioscience has successfully repurposed Niclosamide for Dengue antiviral through its patented drug delivery system technology using inorganics and polymers that are harmless to the human body. With its proprietary technology, Hyundai Bioscience has overcome the challenges of low bioavailability and short half-life of Niclosamide which has pan-serotype antiviral efficacy against Dengue according to the past in vitro studies. Hyundai Bioscience completed the development of a Niclosamide-based formulation for Dengue treatment, which enables drug concentration at 50% viral inhibition level (IC 50) or higher to inhibit the proliferation of four serotypes of the Dengue virus as well as Zika, Chikungunya, and Yellow fever viruses. Hyundai Bioscience stated that Dengue can be treated effectively if the antiviral is administered early stage of the infection before the viral load rapidly increases. Early treatment may be possible if the drug can treat not only Dengue but also other mosquito-borne viral infections such as Zika and Chikungunya that show similar symptoms to Dengue. The new Niclosamide-based Dengue antiviral formulated by Hyundai Bioscience has a broad-spectrum antiviral efficacy that can treat not only Dengue infection but other mosquito-borne viral infections; hence, early and effective Dengue treatment may be possible with effective early administration before a rapid viral load increase. Hyundai Bioscience plans to conduct a basket-type clinical trial in Brazil (confirmatory clinical study for Dengue and exploratory clinical study for other mosquito-borne viral infections). This involves administering the antiviral early to patients infected by any of the four serotypes of the Dengue virus as well as those infected by other mosquito-borne viruses such as Zika and Chikungunya, and then evaluating the drug's efficacy in the Dengue-confirmed patient population. According to the World Health Organization (WHO)'s announcement on March 28, 2024, the number of Dengue cases in the Americas reached 3,578,414 in 2024, with 1,039 deaths. This figure is 3 times the number of Dengue cases reported at the same time in 2023. The global market for Dengue treatments is expected to grow from $880 million in 2023 to $5.4 billion by 2033. "The success of Dengue clinical study on our Niclosamide-based antiviral could lead to its emergency use authorization not only in Brazil but also in other countries. We plan to set the supply price in the $100 range", said Dr. Kim Kyung-Il, CEO of Hyundai Bioscience USA. About Hyundai Bioscience Hyundai Bioscience is a biotechnology company that develops new drugs based on its novel drug delivery system technologies to deliver active ingredients safely and efficiently to targeted areas of the human body. Founded in 2000, Hyundai Bioscience focuses on repurposing or expanding indications of existing drugs using its proprietary organic-inorganic hybrid technologies. Hyundai Bioscience is a public company listed on KOSDAQ (symbol: 048410) in South Korea. For more information, please contact Ms. Joobin Jung, Global PR Manager (joobin@hyundaibio.com).
KUALA LUMPUR, Malaysia, April 25, 2024 /PRNewswire/ -- Universiti Teknologi Malaysia (UTM) has been designated as Malaysia's Erasmus+ National Focal Point and celebrated the launch of the Erasmus+ Malaysia Hub in conjunction with the Ambassadors' Roundtable 2024, organized by UTM's International Office. UTM’s Vice-Chancellor, pictured here alongside some of notable figures at the launching of the Erasmus+ Malaysia Hub in conjunction with the Ambassadors’ Roundtable 2024 Themed "The Odes of Innovating Solutions: Transfiguring Globalization in Higher Education," the event was officiated by the Deputy Minister of Higher Education, YB Datuk Ts. Mustapha Sakmud, and featured a keynote address by His Excellency Mr. Michalis Rokas, Ambassador and Head of Delegation of the European Union to Malaysia, who highlighted the importance of the Erasmus+ Malaysia Hub. "The launch of the Erasmus+ Malaysia Hub by Universiti Teknologi Malaysia is a pivotal initiative that not only facilitates deeper bilateral relations between Malaysia and the European Union but also addresses broader global challenges," stated HE Michalis Rokas. "This hub stands as a testament to the power of educational and cultural exchanges to bridge significant gaps—be it in skills, understanding, or addressing sensitive global issues." With the support of the EU and the active participation of numerous ambassadors, this initiative is uniquely positioned to tackle existential challenges and promote international cooperation, marking a significant advancement in global educational diplomacy. Located at UTM Kuala Lumpur, the Erasmus+ Malaysia Hub will serve as a one-stop information and discussion center for all Erasmus+ Malaysia-related matters, aiming to enhance collaboration between universities and diplomatic missions in Malaysia, and offering guidance and mentorship to those in the higher education sector. According to UTM's Vice-Chancellor, Prof Datuk Ir Ts Dr Ahmad Fauzi Ismail, the selection of UTM as the Erasmus+ National Focal Point (ENFP) by MoHE is an exceptional honour for our institution. "We are grateful for this recognition and express our heartfelt appreciation to everyone involved", he added. He is also enthusiastic about strengthening bilateral cooperation between UTM and other institutions nationally and internationally. UTM currently leads four Capacity Building in Higher Education (CBHE) actions supporting international cooperation projects through multilateral partnerships and collaborates with 23 universities from nine countries on various Erasmus+ initiatives. "We welcome Vice-Chancellors and International Offices of Universities to collaborate with us to enhance our visibility in various Erasmus+ initiatives through joint work with esteemed institutions worldwide," he stated. With nearly 5,000 international students, UTM recognizes the importance of maintaining close and ongoing conversations with ambassadors to Malaysia, striving to strengthen, invigorate, and empower Malaysian higher education institutions toward global prominence. One hundred fifty participants attended the Ambassadors' Roundtable 2024, including 18 ambassadors, Vice-Chancellors, and representatives from university international offices across Malaysia. About Universiti Teknologi Malaysia (UTM): Universiti Teknologi Malaysia (UTM) is a leading public research university in Malaysia, dedicated to advancing knowledge and nurturing future leaders. UTM is committed to excellence in education, research, and innovation, making a significant impact on society and industry. As a global institution, UTM is known for its cutting-edge research and its role in developing innovative solutions to global challenges.
BEIJING, April 25, 2024 /PRNewswire/ -- At Auto China 2024, CATL (SZ.300750) unveiled Shenxing PLUS—the world's first LFP battery that achieves a range above 1,000 kilometers with 4C superfast charging. Within eight months after the launch of the Shenxing superfast charging battery in August 2023, CATL has once again pushed the boundaries of LFP battery technology, ushering in the era of superfast charging for the whole industry. Dr. Wu Kai, chief scientist of CATL Shenxing PLUS Gao Huan, CTO of CATL’s China E-car Business CATL product launch 1,000-km Super-Long Range Ensures Worry-free Travel The Shenxing PLUS battery provides users with a super-long range driving experience, exceeding 1,000 kilometers, which means a trip from Beijing to Nanjing without recharging on the road. This allows new energy vehicles to not only meet commuting needs in urban areas but also accommodate long-distance inter-provincial travel. The 1,000-km pure electric range comes from continuous technological breakthroughs. The cathode of Shenxing PLUS is made with a granular gradation technology, which places every nanometer particle in the optimal position to achieve ultra-high compact density. The proprietary 3D honeycomb-shaped material is added to the anode, boosting the energy density while effectively controlling the volume expansion during charge and discharge cycles. The single-piece casing, which is an industry first, optimizes the internal space utilization, allowing the Shenxing PLUS cells to reach an unprecedented energy density level. At the system level, the Shenxing PLUS battery pack has a topological structure optimized on top of module-free CTP 3.0 technology, enhancing the packing efficiency by 7%. Through breakthroughs in materials and structure, the Shenxing battery system's energy density surpasses the 200 Wh/kg threshold for the first time, reaching 205 Wh/kg, making ranges over 1,000 kilometers a reality. Faster Charging Delivers 600 km on 10-minute Charge Aside from offering long range, Shenxing PLUS also charges fast. It can deliver a 600-km range in just 10 minutes of charging, far surpassing the usual batteries available on the market and realizing a true superfast charging speed of one kilometer per second. To achieve the leapfrogging of charging speed, Shenxing PLUS applies technologies including fast lithium-ion conductive coating, the addition of transition metal elements, and new nanometer encapsulation, rendering smoother and more efficient energy transmission between cathode and anode materials. CATL has expanded the overcurrent area and capacity of the terminals in the battery system to rapidly dissipate heat during high-current charging. In terms of BMS core algorithms, CATL's newly-developed AI polarization model can predict and control the charging current in real time, enabling faster and smarter energy replenishment. Superfast Charging Batteries + Network + Services Create a Closed Loop Ecosystem In addition to exceptional new batteries, CATL has also initiated the construction of the Shenxing Superfast Charging Network to build the largest superfast charging service platform in China. CATL is collaborating with industry-leading partners like Star Charge, YKC and Shudao New Energy to provide the most convenient and cost-effective mobility experience for more owners of cars powered by Shenxing superfast charging batteries. CATL is further planned to launch the industry's first Shenxing superfast charging vehicle owners club, operating in over 600 service outlets covering 271 prefecture-level cities in 31 provincial-level regions. It will provide Shenxing vehicle owners with roadside rescue, battery inspection and maintenance, and other services. On its journey of continuous expansion of scientific frontiers and the utmost pursuit of a better life, CATL is ushering in a superfast charging era for new energy vehicles with a closed-loop supercharging ecosystem by integrating superfast charging battery, network, platform, and services.
SINGAPORE, April 25, 2024 /PRNewswire/ -- DECODE Group's subsidiary, Decode Digital Markets USA Inc, has officially obtained a Money Services Business (MSB) registration license from the Financial Crimes Enforcement Network (FinCEN) in the United States. This achievement marks a significant milestone in the group's compliance and professionalism in the global financial services market. It also consolidates DECODE Group's leading position in the global financial market. DECODE Group Successfully Secures U.S. Financial Services License, Strengthening Global Financial Market Position The new license covers all 50 states and territories of the United States, allowing Decode Digital Markets USA Inc to provide a range of financial services including check cashing (including traveler's and money orders), dealing in foreign exchange, issuing money orders, issuing traveler's checks, money transmission, selling money orders, prepaid access and traveler's checks. This registration adds significant legitimacy and operational breadth to DECODE Group's activities in the U.S. and globally. Decode Global's CEO Ivan Lew said, "obtaining the U.S. MSB registration license is a crucial step in DECODE Group's global strategy. It not only allows us to serve in the U.S. market but also assures our clients of higher standards of financial services. We look forward to further expanding our market share and continuing to drive financial technology innovation, all while adhering to U.S. and international financial regulatory standards." As a global financial services company, DECODE Group is dedicated to delivering innovative financial solutions and services. The company operates in multiple countries and regions, each of which has obtained the necessary financial licenses and certifications to ensure safe and reliable services for global clients. With the acquisition of the U.S. MSB license, DECODE Group is set to further expand its service capabilities worldwide. In the future, the group plans to explore new markets and seek similar registrations or licenses in other countries to support and enhance its financial services worldwide. About DECODE Group DECODE Group is a leading international financial services conglomerate, established in 2004 with its central headquarters located in Sydney, Australia. The group holds multiple financial licenses across various countries, including an Australian Financial Services License, and is authorized to provide financial services. DECODE Group operates under the stringent regulatory oversight of esteemed bodies, notably the Australian Securities and Investments Commission (ASIC).
BEIJING, April 25, 2024 /PRNewswire/ -- Chinese President Xi Jinping stressed further efforts to usher in a new stage in the development of China's western region featuring well-coordinated environmental conservation, greater openness and high-quality development, when he chaired a symposium on boosting the development of China's western region in the new era in Southwest China's Chongqing Municipality. Xi, also general secretary of the Communist Party of China Central Committee and chairman of the Central Military Commission, made an inspection tour in Chongqing from Monday to Wednesday. During the visit, he called on Chongqing to further deepen reform and opening up across the board and write its own chapter in advancing Chinese modernization. The remarks and the inspection tour highlighted the great importance the top leader attaches to the development of the western region, which covers more than 70 percent of China's land area and is home to nearly 30 percent of the country's population. The region plays a critical role in China's pursuit of high-quality development and Chinese modernization, and holds great potential in various areas, economists said on Wednesday. During the symposium on Tuesday, Xi said China's western region has seen significant achievements on eco-environmental conservation and restoration over the past five years, but the region's development is still facing difficulties and challenges, according to the Xinhua News Agency. The Chinese President said developing industries that leverage local strengths should be the main focus, adding that efforts are needed to adopt a region-specific approach in developing emerging industries and expedite industrial transformation and upgrade in the western region. Underscoring the importance attached to greater openness, during the inspection tour of Chongqing, Xi also visited an international logistics hub park to learn about the municipality's efforts in accelerating the development of the New International Land-Sea Trade Corridor in west China, according to Xinhua. China's western region covers Chongqing, six provinces and five autonomous regions, including Southwest China's Sichuan and Northwest China's Xinjiang Uygur Autonomous Region, accounting for 21.5 percent of China's GDP. Although the region's development has been lagging behind the country's eastern coastal regions, in recent years development has been picking up pace. Between 2019 and 2023, the region's combined GDP expanded form 20.5 trillion yuan ($2.83 trillion) to 26.9 trillion yuan, with an annual average growth rate of 4.9 percent. "The development in the western region has improved significantly in recent years in terms of infrastructure, industrial upgrade and people's livelihoods," Hu Qimu, a deputy secretary-general of the digital-real economies integration Forum 50, told the Global Times on Wednesday. In terms of industrial development, the western region has also seen rapid development in recent years. The region is home to nine national level strategic emerging industry clusters in areas such as new materials and biomedicine, and five national level advanced manufacturing clusters such as electronic information and aviation. The region's industrial added value has jumped from 5.8 trillion yuan in 2019 to 8.1 trillion yuan in 2023, according to official data. Critical role, vast potential The symposium on Tuesday further highlighted the western region's critical role in China's efforts to bolster both security and development, as well as its enormous potential in areas such as advanced manufacturing and high-level opening-up, economists said. "The region is tasked not only to boost local industrial development with many industries shift from the east to the west and provide support in resources and other areas, but also to play a bigger role in the country's opening-up efforts," Dong Shaopeng, a senior research fellow at the Chongyang Institute for Financial Studies at Renmin University of China, told the Global Times on Wednesday. Dong noted that there is still great room for the western region to expand opening-up by bolstering connectivity with countries and regions through land transport corridors. The western region has developed multiple trade routes with countries and regions in Europe, Central Asia and Southeast Asia in recent years. The New International Land-Sea Trade Corridor, which connects China's western region with Southeast Asian countries, can reach 490 ports in 120 countries and regions as of January 2024, with cargo volume jumping 21 percent year-on-year in 2023, according to official data. Moreover, the western region also plays a crucial role in the China-Europe Freight Train Express. Over the past five years, 35,000 China-Europe freight trains have been launched in the western region, accounting for 50.5 percent of the national total. Thanks to the greater connectivity, the total import and export volume of the western region reached 3.7 trillion yuan in 2023, an increase of 37 percent from 2019. Greater connectivity and openness of the western region is of great importance to the country's efforts to expand high-level opening-up and bolster both security and development, economists said. "Although the capacity of land transport remains relatively low, it has a very high level of security compared to sea transport," Hu said, noting that land transport corridors in the western region can better cope with geopolitical tensions and offer a steady channel for transport of strategic resources under extreme circumstances. Apart from its great importance in China's long-term security and development, the western region is also crucial in the country's efforts to tackle downward pressure and consolidate the economic recovery in the short term by boosting domestic investment and consumption, economists said. "Whether it is from the perspective of responding to international situation, or overall coordination of development and security, or the current need to stabilize growth, it is imperative to boost the development of the western region," Hu said, pointing to the huge potential in infrastructure investment and consumption in the region. As the region's economic development accelerated in recent years, infrastructure construction and consumption has also been expanding steadily. For example, in the first quarter of 2024, Chongqing saw a 4.4-percent growth in fixed-asset investment, with a 16.7-percent growth in industries and 8.5 percent in infrastructure. Retail sales in the municipality also grew by 5.5 percent year-on-year, higher than the national growth rate of 4.7 percent, according to official data.
New DJI Agricultural Drones Launch Globally with Upgraded SmartFarm App SHENZHEN, China, April 25, 2024 /PRNewswire/ -- DJI, the world leader in civilian drones and creative camera technology, today announced the international launch of the Agras T50 and Agras T25 drones. Building on the popular Agras drone line, the T50 offers unmatched efficiency for larger-scale growing operations, while the lightweight T25 is designed to be more portable for smaller fields. Both drones are compatible with the upgraded SmartFarm app which offers powerful features for comprehensive aerial application management. DJI Agras T50 and T25 "As a global leader in agriculture technology, we aim to push precision agriculture forward with the latest DJI Agras drones for spraying and spreading. To date, over 980 million acres worldwide across over 100 countries and regions have been treated by DJI Agriculture drones," said Yuan Zhang, Head of Global Sales at DJI Agriculture. "With our proven solutions for crop protection, family farmers and large-scale growers can improve yields, reduce chemical usage, and cut costs, while minimizing environmental impact." Better Growth with the Agras T50 The Agras T50 is a flagship of efficiency and stability, born from a deep understanding of the demands of large-scale farming. It inherits a coaxial dual-rotor design and 54-inch propellers for next-level stability when carrying 40kg spraying or 50kg spreading payloads, which enables efficient spraying of up to 50 acres (21 hectares) per hour1. T50's dual atomization spraying system, with an increased flow rate of up to 16 liters per minute with two sprinklers and adjustable-sized spray droplets, is ideal for a variety of applications from fields to orchards. Easily converted to its spreading configuration, the T50 can carry 50 kg of dry granules and spread at a flow rate of up to 108 kg/min1 or 1.5 tonnes per hour1. This combination of power, precision, and versatility sets T50 apart as a top choice in agricultural drones, designed to meet the evolving needs of modern farming. Breakthroughs in Connectivity and Stability T50 features an upgraded four-antenna O3 Transmission system, extending the remote controller-drone connection up to 2 km1. For operations over mountains and other complex environments, users can deploy a DJI Relay to extend transmission range and stability for improved operation safety. Dual Radar and Dual Binocular Vision for Obstacle Bypassing and Terrain Following T50 features dual Active Phased Array Radars and binocular vision sensors. These work together to accurately reconstruct the T50's surroundings and detect nearby obstacles, for intelligent obstacle sensing and bypassing, and Terrain Following over slopes. Four Sprinkler Kit T50 can be equipped with an additional pair of centrifugal sprinklers, increasing flow rate to 24 liters per minute. This benefits tasks like orchard spraying that require a higher flow rate to penetrate dense canopies and treat the fronts and backs of leaves. 9-Minute Fast Charging T50 is powered by a DB1560 Intelligent Flight Battery, with a capacity of up to 30 Ah and 1500 charge cycles1. The D12000iEP Multifunctional Inverter Generator paired with the Air-Cooled Heat Sink enables 9-minutes1 fast charging, allowing for continuous operations with a pair of batteries. Agras T25 - Precision Agriculture in a Portable Package The Agras T25 packs all the advanced features of the T50 into a smaller, portable design. It can carry a 20kg spraying or 25kg spreading payload and includes the T50's top features like multidirectional obstacle avoidance, Terrain Following, ultra-fast battery charging, one-tap takeoffs, and automatic operations. This makes it perfect for solo use in small to medium-sized farms. DJI SmartFarm - Essential Agras Assistant The DJI SmartFarm app streamlines daily drone operations for crop protection and plot management with enhanced data visualization and reporting, a dynamic device management dashboard, and easy access to after sales support and learning resources on DJI Academy. Availability The Agras T50 and T25 can now be reserved starting April 25. Interested buyers can get pricing from local authorized DJI Agriculture dealers. Learn more: ag.dji.com/t50 and ag.dji.com/t25. 1 All data was measured using a production model in a controlled environment. For more information, please refer to our official website: ag.dji.com For more information, visit our:Website: ag.dji.comFacebook: facebook.com/DJIAgricultureTwitter: twitter.com/DJIAgricultureYouTube: youtube.com/@DJIAgricultureInstagram: instagram.com/dji.agras
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