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New state-of-the-art facility to develop immunotherapy assets to address unmet needs in cancer treatmentSINGAPORE - Media OutReach - 28 June 2023 – Biosyngen, an immuno-oncology company with technology targeting the unmet medical needs in solid tumour and lymphoma treatment, today announced the official opening of its latest Good Manufacturing Practice (GMP) facility in Singapore. The facility will support cell manufacturing for immunotherapies in Singapore and across the world, and create more than 200 jobs for the cell and gene therapy (CGT) industry in the next three to five years. [From Left to Right] Dr Han Deping, Chief Medical Officer, Biosyngen; Dr Cheong Wei Yang, Deputy Secretary (Technology), Ministry of Health; Ms Joan Zhang, Chairman, Biosyngen; Mr Alvin Tan, Minister of State for the Ministry of Trade & Industry; Ms Lily Peng Yuemei, Deputy Party Secretary, Director, Knowledge City (Guangzhou) Investment Group and Dr Michelle Chen, Chief Operating Officer, Biosyngen The opening was officiated by Mr Alvin Tan, Minister of State for the Ministry of Trade and Industry, and executives from Biosyngen including Ms Joan Zhang, Chairman of Biosyngen, Prof Benjamin Seet, Board Member of Biosyngen, Dr Michelle Chen, Chief Operating Officer of Biosyngen and Prof Jean Paul Thiery, Chief Scientist of Biosyngen. The opening was also witnessed by distinguished guests from the Ministry of Health, Enterprise Singapore, Economic Development Board, SGX, A*STAR and National Cancer Centre Singapore (NCCS). The new facility is the first and largest privately-owned, fully automatic, enclosed and integrated GMP cell manufacturing facility and Research & Development base in Singapore to date. The facility is compliant with the latest FDA (U.S. Food and Drug Administration) recommendation, enabling Biosyngen to run automatic and closed-system production – the preferred best practice in the CGT industry. Designed with containment within each production suite, this facility can support multiple clinical trials in parallel. According to statistics from The Global Cancer Observatory (GCO), there were over five million deaths due to solid tumour cancers in Asia in 2020, accounting for 60% of the world's mortality rate.[1] Most solid tumours respond poorly to conventional cancer treatments such as chemotherapy.[2] Biosyngen's new GMP facility will leverage innovative capabilities to further the development of cutting-edge immunotherapies to improve treatment outcomes for such solid tumours. "We started from humble beginnings in Singapore, renting a facility from Temasek Life Sciences Laboratory, and have now launched our new GMP facility. There is an urgency to increase speed in clinical trials for patients and build capacity for global needs, and Biosyngen is determined to take the lead in this space," said Dr Michelle Chen, Chief Operating Officer, Biosyngen. Through years of extensive research, Biosyngen's first-in-class products targeting nasopharyngeal cancer (NPC) and EBV+ lymphoma were granted Investigative New Drug (IND) approval by the US FDA and China National Medical Products Administration (NMPA). Its product targeting NPC was also recently granted the status of Orphan Drug Designation (ODD). In June 2023, the company submitted IND applications for two other indications, lung cancer and liver cancer, to both the FDA and NMPA. "Our facility in Singapore enables R&D in drug discovery and process development, and will also be able to accommodate more advanced processes or products that will be introduced in the future," added Dr Cecilia Zhang, Chief Scientific Officer, Biosyngen. In Guangzhou China, Biosyngen also has the largest GMP cell production base in South China. Biosyngen has become the only immuno-oncology company in Asia with dual headquarters, dual fully automatic and enclosed GMP, and dual R&D layout. Biosyngen has achieved the simultaneous global development of innovative drugs and cost reduction of CGT drugs to the largest extent. "We are a company dedicated to giving cancer patients a new lease of life by developing first-in-class immunotherapies. We aim to achieve this through our Research & Development (R&D) and collaborations with key stakeholders in hospitals, the wider industry and governments. Having two sites, one in Singapore and China, is a key global strategy for Biosyngen to advance the company's product pipeline quicker, and drive R&D and GMP manufacturing from both sites," said Isaac Chow, Chief Business Officer, Biosyngen. Earlier this week, the company signed two key agreements to set up a China-Singapore Technology Innovation and Translational Medicine Centre for Tumour Prevention and Treatment as part of the Singapore-Guangdong Collaboration Council (SGCC), and a joint lab with Agency for Science, Technology and Research (A*STAR) to develop multi-specific antibodies targeting solid tumours as part of the Singapore Economic and Trade Cooperation Council. Biosyngen is also working closely with stakeholders in the Singapore healthcare ecosystem, collaborating with the National Cancer Centre Singapore (NCCS) to conduct a basket of clinical trials for various cancer indications and biomarker discovery to enhance patient selection and effectiveness. In addition, the company has partnered with the Agency for Science, Technology and Research (A*STAR) to develop multi-specific antibodies targeting solid tumours. The company also works closely with the Advanced Cell Therapy and Research Institute (ACTRIS) to consult on GMP practices and process development. [1] https://novotech-cro.com/sites/default/files/2022-07/Novotech_DiseaseReport_SOLIDTUMORS_APAC_CT_LANDSCAPE.pdf [2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852245/ Hashtag: #biosyngen #celltherapy #gmpfacility #immuno-oncologyhttps://www.linkedin.com/company/biosyngen/The issuer is solely responsible for the content of this announcement.About BiosyngenWith R&D powered by scientists from Singapore, China, Germany, Australia, France, and America, Biosyngen is dedicated to give cancer patients a second chance by developing first-in-class innovative immunotherapies. Aiming for the global market with dual R&D centers and GMP facilities set in Singapore and China, Biosyngen owns a product portfolio with potential global market of more than 50 billion USD. Biosyngen possesses exclusive licenses and patented therapies targeting multiple solid tumors and hematological malignancies including nasopharyngeal cancer, gastric cancer, lymphoma and posttransplant lymphoproliferative disorders. We collaborate closely with the world's leading biomedical research and clinical institutes including A*STAR, Helmholtz Zentrum München, Hannover Medical School, Sun Yat-Sen University Cancer Center to advance our R&D process and conduct clinical trials in Singapore, Australia and China. Utilizing our strong R&D capability and translational medicine platform, we have been able to engage the end-to-end cycle of drug development including lead identification, preclinical studies cell production and quality control, regulatory filing and clinical studies, thus integrating R&D, manufacturing and commercialization
TOKYO, June 28, 2023 /PRNewswire/ -- Kyoraku Co., Ltd. (hereunder "Kyoraku"), a Tokyo-based developer of foamed ducts widely used in commercially supplied vehicles, has succeeded in obtaining measurement data from an actual vehicle regarding the effect of improving electricity consumption by using foamed ducts as instrument panel ducts for electric vehicle (EV) air-conditioners. In the past, foamed ducts were known to improve insulation performance and contribute to fuel efficiency improvement in gasoline-powered vehicles, but it is the first time (*) that an EV has actually run to demonstrate the electric cost effect by using foamed ducts.(Measured by Japan Automobile Research Institute (JARI))(*) Kyoraku's research Image:https://cdn.kyodonewsprwire.jp/prwfile/release/M107755/202306216512/_prw_PI1fl_rL4JoE39.png Measurement results summary Mileage was compared in the distance from the status of a full charge to the appearance of an indicator of power supply requirement in a commercially supplied EV under the conditions of running over WLTC mode 3 cycles and heating in winter, followed by steady running at 100 km/h. As a result, it was demonstrated that the mileage improved 2.4% by using Kyoraku's polypropylene (PP)-based 4 times foamed duct (3 mm thick), compared with the conventional polyethylene (PE) instrument panel duct (0.8 mm thick). It was also demonstrated that the mileage improved 1.6% in a PE 4 times foamed duct (3 mm thick), which was newly made available for mass production. In the same driving experiment, when comparing battery consumption at the end of a WLTC 3-cycle run (approximately 45 km, an identical driving distance), the use of the PP foamed duct reduced battery consumption 0.79% compared with the conventional PE duct, and a 0.39% reduction in usage was also demonstrated for the PE foamed duct. *Battery usage and reduction rates were calculated by Kyoraku based on OBD diagnostic machine information. In the past, there have been needs for the foaming of automotive air-conditioner ducts to reduce weight, and this demonstration of power cost-effectiveness is expected to further increase their appeal. Kyoraku, ready to open its doors to this foamed duct technology to the world, is looking for global partners. About Kyoraku Kyoraku Co., Ltd. is a well-established integrated company which has been manufacturing and selling plastic products for over 100 years. It is active in industries requiring high-quality, special plastics, such as medical/food containers and automobile parts. As a pioneer and comprehensive company in plastics, it hopes to continue to be the best partner behind the scenes to help create a better environment-friendly society with its advanced proprietary technologies and distinctive products created from them. Company profile- Name: Kyoraku Co., Ltd.- Established: September 20, 1917- Representative: Takamitsu Nagase, Executive Board Director, President- Head office: 1-5, Higashinihonbashi 1-Chome, Chuo-ku, Tokyo 103-0004, Japan- URL: https://www.krk.co.jp/en/- Business profile: Manufacturing, processing and sales of plastic products
Two-day Event Provides Primer on Latest Internet Security and DNS Industry Trends SINGAPORE, June 28, 2023 /PRNewswire/ -- The second Asia Pacific (APAC) Domain Name System (DNS) Forum 2023 will be held on 4–5 July 2023 at the Hong Kong Convention and Exhibition Centre in Hong Kong. Approximately 400 people from the Asia Pacific region have registered for the hybrid event, which will take place in Hong Kong for the first time. The forum is co-organized by the Hong Kong Internet Registration Corporation Limited (HKIRC) and the Internet Corporation for Assigned Names and Numbers (ICANN). HKIRC The event will bring together experts from different fields, including DNS architects, network engineers, cybersecurity experts, and business leaders. The forum provides a platform for stakeholders from around the world to convene and discuss issues related to the latest Internet developments, such as DNS abuse, big data applications, digital transformation, cybersecurity, and the marketization of Internet infrastructure. "The DNS is the fundamental 'glue' that holds the Internet together. Continued growth of the Internet, as well as emerging technologies and services, all rely on the Internet's unique Identifier systems, which ICANN helps to keep working through its coordination role. We look forward to sharing more on this with the participants," said ICANN Senior Vice President and Chief Technology Officer, John Crain. Expressing his pleasure with working with ICANN, HKIRC Chairman Simon Chan, B.B.S., J.P. said, "We are honored to work with ICANN to host this regional event in Hong Kong. As a leading player in the Internet industry, HKIRC is committed to promoting the development of a secure, stable, and resilient Internet infrastructure in Hong Kong and beyond. This event provides a unique opportunity to bring together industry experts to discuss critical issues facing the Internet today." The forum features a range of topics related to the diverse applications of DNS and its significance in shaping the digital landscape, with particular emphasis on the contribution of DNS to digital transformation and the digital economy. One of the key topics to be discussed at the event is cyber-attacks and DNS abuse. Experts will highlight the importance of implementing comprehensive security measures and DNS management practices to prevent cyber-attacks and DNS abuse, which are two different but related issues that organizations need to be aware of in today's digital environment. Attendees will gain actionable insights on how to combat these threats and protect their DNS infrastructure. The forum will also showcase the latest trends and innovations in big data, digital infrastructure, blockchain technology, and artificial intelligence. These developments offer great potential to facilitate the adoption of big data, digital infrastructure, and the digital economy, encouraging users to embrace the digital future. Attendees will be provided with practical strategies for success in these areas. The growth of the Internet has played a key role in fostering the digital economy, digital infrastructure, and promoting smart cities. As technology continues to advance, the importance of the Internet and digital infrastructure is likely to only continue to grow, providing new opportunities for economic growth and improving the quality of life for people in cities around the world. Visit the APAC DNS Forum 2023 website for more information. Registration is free and required to attend the event (virtually or in person). The closing date for registration is 2 July 2023. About ICANN ICANN's mission is to help ensure a stable, secure, and unified global Internet. To reach another person on the Internet, you have to type an address - a name or a number - into your computer or other device. That address must be unique, so computers know where to find each other. ICANN helps coordinate and support these unique identifiers across the world. ICANN was formed in 1998 as a not-for-profit public-benefit corporation and a community with participants from all over the world. About HKIRC Hong Kong Internet Registration Corporation Limited (HKIRC) is a not-for-profit and non- statutory corporation designated by the HKSAR Government to administer the registration of Internet domain names under .hk and country-code top level domains. HKIRC provides registration services through its registrars for domain names ending with .com.hk, .org.hk, .gov.hk, .edu.hk, .net.hk, .idv.hk, 公司.香港, .組織.香港, .政府.香港, .教育.香港, .網絡.香港, .個人.香港, .hk and .香港.
The 2023 DigiconAsia DX Solution Excellence Awards honors APAC's digital innovators for providing transformative solutions and services across various industry sectors. SINGAPORE, June 28, 2023 /PRNewswire/ -- In the midst of a tumultuous pandemic and an acute global technology talent shortage, many organizations have accelerated their digital business transformation projects to adapt their workplace, workforce and business operations to the demands of an economy in crisis. However, in the never-ending digital transformation (DX) journey, the heroes working in the background to provide these transformative and innovative digital solutions to meet the needs and demands of specific industries are rarely recognized. Last year's DX Solution Excellence Awards aimed to change this, by recognizing and honoring solution providers that have made a major impact in transforming organizations in various vertical industries. This year's DigiconAsia DX Solution Excellence Awards continues that tradition with 36 shortlisted nominations for 9 industry categories. 152 of our readers – largely decision makers in enterprise end-user organizations – cast their votes, based on the solution summary and references submitted by the nominees, using the following criteria: Innovative features of the DX-related solution that meet specific industry sector needs and demands in Asia Pacific Ability of the solution/service to: enhance employee and/or customer experience Improve operational efficiencies and/or productivity Contribute effectively to business performance/profitability Users' feedback on the deployment of the solution or service And the winners are… Digital Innovator of the Year – Arts, Entertainment & MediaHashiCorp Digital Innovator of the Year – Business ServicesSecuronix Digital Innovator of the Year – Education & TrainingAlcatel-Lucent Enterprise Digital Innovator of the Year – Energy, Utilities, Agriculture & MiningPrinceton Digital Group Digital Innovator of the Year – Financial Services & InsuranceInformatica S.E.A. Pte Ltd Digital Innovator of the Year – Healthcare & PharmaceuticalSmartRx Digital Innovator of the Year – Logistics, Transport & Supply ChainFusionex Group Digital Innovator of the Year – ManufacturingZebra Technologies Digital Innovator of the Year – Wholesale & RetailCanon Singapore Pte Ltd Check out https://www.digiconasia.net/dx-solution-excellence-awards-2023 to find out which innovative solutions from these providers won, and why… "In uncertain times, the 2023 DigiconAsia DX Solution Excellence Awards program plays an important role to identify and highlight the solution providers, innovators and forward-looking users behind the digital transformation successes among organizations and across industries in Asia Pacific," said Victor Ng, Editor-in-Chief of DigiconAsia. "It's our privilege to showcase and honor the innovations and technologies Asia Pacific's digital technology leaders have developed to serve as the pillars of the digital economy, enabling and accelerating that continuous transformation journey in an increasingly hybrid, complex and uncertain business world."
The number of investors with more than 25% of their portfolio invested in ETFs is up 11% from 2022 Hong Kong, June 27, 2023 – Greater China ETF investors are expanding their usage of ETFs and accessing new and diverse products, despite challenging market conditions, according to the findings of the 6th Annual Greater China ETF Investor Survey from Brown Brothers Harriman & Co. (BBH), a global ETF custodian and administrator. The report, released today, is a subset of BBH's 10th Annual Global ETF Investor report, and represents the opinions of more than 100 institutional investors, financial advisors and fund managers from the Mainland, Hong Kong and Taiwan. In total, 59% of respondents manage over USD 1 billion in assets. Key Findings: ETFs are integral components of investors' portfolios: Investors in Greater China continue to allocate capital to ETFs and 75% of investors expect their use of ETFs to increase this year. Mainland investors' demand for Hong Kong listed ETFs increases: 69% of these investors purchase Hong Kong listed ETFs through the existing cross-border programs. 62% of Mainland investors are interested in managed risk strategies, while 43% prefer ESG or thematic strategies via ETF inclusion in Stock Connect. Thematic ETFs expand their reign: Over 90% of investors are planning to increase or maintain their exposure in thematic ETFs. Internet/Technology, Robotics & AI and ESG are the top three thematic strategies in demand. Flight to safety continues: Given market volatility, 85% of investors in the region prefer managed risk strategies. 79% of investors also expect to increase their exposure to ETFs with dividend/income strategies. Macro trends fuel appetite for fixed income: Investors are turning to fixed income ETFs at a rapid rate due to the interest rate environment. 50% of investors are planning to allocate to fixed income ETFs this year with short duration/money market exposure being the top choice. Optimistic about ESG: 62% of investors in the region are planning to allocate to ESG investments. In terms of ESG ETFs, most investors are evaluating products by reviewing company statements/reports for underlying holdings. Active is on the rise: 50% of investors allocated from index and active mutual funds to actively managed ETFs. 88% of investors plan to increase or maintain their exposure in actively managed ETFs as more of these products are introduced. Investors use ETFs to adapt strategy: As portfolios shift to align with the market cycle, respondents are using smart beta ETFs to mitigate risk (65%), reduce volatility (54%) and generate income (49%). "Despite market turbulence, investors in the region are turning to ETFs as tools to navigate risk and diversify portfolios. ETFs are playing an increasingly vital role in investors' asset allocation strategies and our survey highlights the resounding interest from investors across a wide range of strategies and asset classes," said Chris Pigott, Asia Head of ETF Services at BBH. "The responses support that the ETF wrapper is an optimal vehicle for a wide range of exposures and we are seeing asset managers listing a diverse set of products in the region. Investors across the region do have different approaches to selecting ETFs or how they access the product, and throughout the survey we focus on these nuances that asset managers need to consider as part of their ETF strategy." Read the full report here: 2023 Greater China ETF Investor Survey. Hashtag: #BBHThe issuer is solely responsible for the content of this announcement.About Brown Brothers HarrimanBBH is an independent, global financial services firm founded in 1818 and headquartered in New York City. It counts among its clients institutions, privately-held companies, families and wealthy individuals which it serves through its three business lines: Investor Services, Investment Management and Private Banking. The firm is known for its exceptional client service and selectivity. BBH's Investor Services business provides cross-border custody, accounting, administration, execution and advanced technology services to many of the world's leading asset managers and financial institutions. BBH's Investment Management and Private Banking businesses manage public and private securities portfolios, advise banking clients on strategic direction, provide debt financing and banking services and offer trust and estate services. BBH, including BBH Investor Services, operates in over 90 markets worldwide from 18 offices. BBH employs approximately 6,000 professionals. For more information, please visit www.bbh.com. Disclaimer Brown Brothers Harriman & Co. ("BBH") may be used as a generic term to reference the company as a whole and/or its various subsidiaries generally. This material and any products or services may be issued or provided in multiple jurisdictions by duly authorized and regulated subsidiaries. This material is for general information and reference purposes only and does not constitute legal, tax or investment advice and is not intended as an offer to sell, or a solicitation to buy securities, services or investment products. Any reference to tax matters is not intended to be used, and may not be used, for purposes of avoiding penalties under the U.S. Internal Revenue Code, or other applicable tax regimes, or for promotion, marketing or recommendation to third parties. All information has been obtained from sources believed to be reliable, but accuracy is not guaranteed, and reliance should not be placed on the information presented. This material may not be reproduced, copied or transmitted, or any of the content disclosed to third parties, without the permission of BBH. All trademarks and service marks included are the property of BBH or their respective owners. © Brown Brothers Harriman & Co. 2023. All rights reserved. IS-09007-2023-06-16
Gaw NP Industrial is expanding its horizons with GNP Dong Van 3 – Industrial Center, a 160,000 sq. m ready-built factory and warehouse facility in Ha Nam province, a rising FDI hub in Northern Vietnam. HANOI, Vietnam, June 28, 2023 /PRNewswire/ -- The project is empowered by Gaw NP Capital, a 200 USD million platform backed by Gaw Capital Partners, which is a global real estate private equity firm, a uniquely positioned private equity fund management company focusing on real estate markets in Asia Pacific and other high barrier-to-entry markets globally; along with NP Capital Partners, a reputable real estate firm with a strong network and development capability in Vietnam. Situated in Dong Van 3 industrial park, Ha Nam province, GNP Dong Van 3 – Industrial Center provides state-of-the-art industrial facilities to cater the increased storage and production needs. Spaces are highly flexible and can evolve with business needs starting from 2,500 sq. m for ready-built factory and 9,100 sq. m for warehouse. The ready-built factories and warehouses feature advanced fire prevention and fighting systems and completely open factory floor plans with no internal columns to maximize the operation capacity of manufacture. Tenants can also rely on all-in-one supporting facilities such as wide internal roads, 24/7 camera surveillance and on-duty security personnel, a truck court, a spacious parking area, and an integrated sewage treatment plant. The site's distinctive advantage lies in its strategic positioning at the heart of the North Central region. It provides convenient access to major routes, including National Highway 1A, Cau Gie-Ninh Binh Expressway, National Highway 38, and the North-South Expressway. Reaching Hanoi CBD within 45 minutes, 80 minutes to Noi Bai International Airport and 120 minutes to Hai Phong Sea Port, this strategic position as a transportation hub offers unparalleled benefits to businesses looking to establish a foothold in Vietnam. GNP Dong Van 3, scheduled for handover in Q4 2023, is perfectly suited to cater the rising demand driven by the supply chain of neighboring industry leaders such as Honda, YKK, Wistron, Qisda, Seoul Semiconductor, and other manufacturing from Taiwan, Japan and South Korea. In addition, tenants can take advantage of the robust population in Ha Nam province, providing a total labor force of nearly 480,000 people and 14,000 joining the workforce every year. For further information, visit www.gawnpcapital.vn/industrial/ Contact: Hotline: (+84) 789 75 77 88 Email: info@gawnpindustrial.vn
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