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CAMBRIDGE, Mass., ROTTERDAM, Netherlands and SHANGHAI, Feb. 20, 2025 /PRNewswire/ -- Harbour BioMed (HKEX: 02142, the "Company"), a global biopharmaceutical company committed to the discovery, development and commercialization of novel antibody therapeutics focusing on immunology and oncology, and Insilico Medicine ("Insilico"), a clinical stage generative artificial intelligence (AI)-driven biotechnology company, today announced a strategic collaboration to accelerate the discovery and development of innovative therapeutic antibodies, leveraging their respective technological strengths in antibody discovery and artificial intelligence. Under the collaboration agreement, the parties will combine Harbour BioMed's industry-leading technology platform, proprietary dataset and extensive expertise in antibody development with Insilico's advanced capabilities in designing integrated AI-driven drug discovery and development platforms to jointly develop the next-generation AI-powered antibody application. Additionally, the two companies will collaborate on early-stage drug discovery programs targeting novel, specific antibodies, leveraging Insilico's AI expertise and Harbour BioMed's wet lab capabilities. These efforts aim to deliver innovative therapeutic solutions for the unmet medical needs of immunology, oncology, and neuroscience. Harbour BioMed has built a strong foundation in antibody discovery and development, underpinned by its advanced technology platform, proprietary dataset, and deep expertise. The Company's proprietary Harbour Mice® platform enables the generation of fully human monoclonal antibodies in both conventional (H2L2) and heavy chain-only (HCAb) formats, eliminating the need for additional engineering or humanization. The HCAb technology, in particular, produces unique, fully human heavy chain-only antibodies that are approximately half the size of conventional IgGs, offering significant advantages for next-generation antibody therapies. With a clinically validated and globally recognized platform, Harbour BioMed has applied its technology in more than 250 drug discovery programs across various therapeutic areas, establishing itself as a leader in the field of biotherapeutics. Insilico has previously showcased the capability of its proprietary AI platform to significantly reduce cost and improve efficiency in the early stages of small molecule drug discovery and development. Since 2021, the company has established a wholly-owned pipeline of 30 assets powered by its Pharma.AI platform, 10 of which have received IND clearance, setting a benchmark for AI-driven drug discovery and development. In July 2024, Insilico introduced Generative Biologics, an AI-powered tool for de novo protein engineering, designed to accelerate the development of next-generation biologics. Moving forward, the company plans to leverage real-world case studies to further refine and advance the application through ongoing enhancements and iterative improvements. "We are excited to collaborate with Insilico, a pioneer and leading advocate in AI-driven drug discovery and development, to integrate AI technologies with our industry-leading technology platform and proven expertise in antibody discovery and development," said Jingsong Wang, MD, PhD, Founder, Chairman, and CEO of Harbour BioMed. "By combining our validated Harbour Mice® platform with advanced generative AI approaches, we aim to further streamline antibody discovery, enhance candidate selection, and ultimately bring innovative therapies to patients more efficiently." "By combining advanced machine learning models with biological expertise, AI platforms are transforming antibody discovery and engineering - enabling the prediction of antibody structures, identification of binding sites, and design of candidates with enhanced specificity, efficacy, and safety," said Feng Ren, PhD, Co-CEO and Chief Scientific Officer of Insilico Medicine. "High-quality dataset and wet-lab validation are critical components in this process, and we are thrilled to collaborate with Harbour BioMed who excel in these areas. Together, we aim to build the next generation AI-driven antibody platforms and deliver breakthrough antibody therapies to address critical healthcare needs." About Harbour BioMed Harbour BioMed (HKEX: 02142) is a global biopharmaceutical company committed to the discovery, development, and commercialization of novel antibody therapeutics focusing on immunology and oncology. The Company is building its robust portfolio and differentiated pipeline through internal R&D capability, collaborations with co-discovery and co-development partners, and select acquisitions. The proprietary antibody technology platform Harbour Mice® generates fully human monoclonal antibodies in two heavy and two light chains (H2L2) format, as well as heavy chain only (HCAb) format. Building upon the HCAb antibodies, the HCAb-based immune cell engagers (HBICE®) bispecific antibody technology is capable of delivering tumor-killing effects unachievable by traditional combination therapies. Integrating Harbour Mice®, and HBICE® with a single B cell cloning platform, our antibody discovery engine is highly unique and efficient for the development of next-generation therapeutic antibodies. For further information, please refer to www.harbourbiomed.com. About Insilico Medicine Insilico Medicine, a global clinical stage biotechnology company powered by generative AI, is connecting biology, chemistry, medicine and science research using next-generation AI systems. The company has developed AI platforms that utilize deep generative models, reinforcement learning, transformers, and other modern machine learning techniques for novel target discovery and the generation of novel molecular structures with desired properties. Insilico Medicine is developing breakthrough solutions to discover and develop innovative drugs for cancer, fibrosis, central nervous system diseases, infectious diseases, autoimmune diseases, and aging-related diseases. www.insilico.com
SHANGHAI, Feb. 20, 2025 /PRNewswire/ -- Hotel & Shop Plus, organized by IM Sinoexpo, gathers leading suppliers from construction and operation sector under one roof to present their latest products, services and innovative developments for hotels, restaurants, shopping malls and all commercial facilities. It will be held at SNIEC in Shanghai from March 31 to April 3, 2025. Our exhibit categories include hotel building, hotel supplies, smart hotel, commercial cleaning. In 2025, the hotel industry is shifting focus towards enhancing customer experience, operational efficiency, and space design. Creating symbiotic experiences through design has become a key issue for the industry to address. In this context, Hotel & Shop Plus will organize various exciting events with the theme of "Ecology • Symbiosis," such as the China International Building & Interior Design Forum and the China International Lighting Design Forum. These events will bring together experts to explore the future of the hotel industry. 2025 Speaker Lineup Released: Chris Godfrey, Co-CEO of HBA Mark Eacott, Global Design Vice President of Ennismore Hotel Group Eirc W. Tsay, Founder of Studio STAY Shanshan Qi, Principal, STUDIO QI ARCHITECTS Mai Chongchaiyo, Chief Creative Director of Steve Leung Hospitality Limited Martin Klaasen, Managing Partner of Nulty Group Emmanuel Clair, CEO & Chief Lighting Designer of Light Cibles Wan Jun Bai, General Manager & Creative Director of Bamboo Lighting Design At Hotel & Shop Plus, top exhibitors will showcase innovative products and solutions. For example, ARROW will provide high - quality intelligent sanitary solutions for hotel clients. Its new products, such as the X7 smart toilet and the YURI urinal, demonstrate the perfect blend of technology and quality, heralding a new era of smart bathroom solutions. Exhibitors in the building materials category, including Jomoo, Simon, Johnson, Longsheng, FUSA, Lanshen, SANGO, Saintly, Kinda Signage, and Nason, have all confirmed their attendance at the event. High-quality linens and supplies enhance guest comfort, positive reviews, and repeat visits. Many exhibitors of hotel supplies and textiles have also brought high-quality products, including Groupe GM, LE LABO, ADA, La Bottega, LANVIN, CANASIN SIDEFU, AMERICA STANDARD, GOLDENSAIL, etc., bringing a broader vision to the exhibition and more development opportunities for hoteliers. Registration and Participation Click here to register free for Hotel & Shop Plus 2025. Discover trends, network, & seize opportunities at this event. https://reg.hdeexpo.com/?utm_source=media&utm_medium=social&utm_campaign=PRNEWSWIRE3 For queries, email: jade.liao@imsinoexpo.com. Visit: Hotel & Shop Plus
As Japan's top crypto tax service, trusted by more than 150,000 users since 2017, cryptact is now available in Canada – offering reliable tax reports at a campaign price of US$22.50. Founded by former Goldman Sachs executives, cryptact brings institutional-grade expertise to simplify cryptocurrency tax filing with accuracy and efficiency. TORONTO, Feb. 13, 2025 /PRNewswire/ -- pafin Inc. (Co-CEOs Amin Azmoudeh and Gaku Saito), the provider of cryptact, a leading cryptocurrency calculation service for tax filing, today announced its official launch in Canada. Founded by former Goldman Sachs executives with extensive experience in finance and investment, cryptact leverages institutional-level expertise to deliver accurate and efficient crypto tax solutions. cryptact_Crypto tax calculations: Simplified. To mark this milestone, cryptact is offering a 50% discount on paid plans until April 30, 2025. Key Features of cryptact Japan's leading crypto tax service: since 2017, cryptact has been the most trusted crypto tax service in Japan, serving more than 150,000 users. Developed by a multicultural startup based in Tokyo, it is built by a team of experts in finance, technology, and blockchain. Wide support for exchanges and coins: cryptact supports 24,000+ cryptocurrencies across 137 exchanges and blockchains, offering one of the broadest coverages among crypto tax service providers. Comprehensive free access: users can start calculating capital gains, losses and income for exchanges, DeFi, and NFTs, and import up to 100,000 transactions per year – all for free. The most affordable tax reports: with a 50% discount, "Basic" plan, normally priced at US$45, is now available for just US$22.50 – offering one of the best values among crypto tax service providers. All past tax years covered: by purchasing an annual subscription, users can calculate profit and loss for any year, making it an accessible option for those filing a tax return for the first time. Accurate and reliable calculations: developed in collaboration with MetaCounts, a Canadian crypto tax expert, cryptact provides precise calculations for a wide range of transaction types. Automatic identification of DeFi and NFT transaction types: users can simply input a wallet address, and cryptact will automatically import all transaction history and identify transaction types, significantly reducing manual work. Seamless transition from other services: no past transaction history is required. Users can get started by entering only the cryptocurrencies held as of January 1st of the tax year and their cost basis. Service page: start using our services for free with just your email address. https://www.cryptact.com/en About the Canada Launch Campaign Eligible Users: Residents of Canada Offer： 50% off on new purchases or plan upgrades for all plans (excluding the Data Retention Plan) How to Apply the Discount： No coupon code required – simply sign up via the service page above, and the discount will be automatically applied at checkout. Offer Period： February 12, 2025 – April 30, 2025, 23:59 EDT Future Outlook "We are committed to continuously improving our services to meet the evolving needs of our users. As a trusted partner for cryptocurrency users in Canada, we will expand support for additional cryptocurrencies, exchanges, and blockchains while introducing new features to further enhance our user experience." said Amin Azmoudeh, Co-CEO, pafin Inc. Leadership Profiles cryptact founder: Amin / Gaku Amin Azmoudeh, Co-CEO After graduating with a BS in Computer Science and a BA in Japanese from the University of Maryland in 2003, Amin joined Goldman Sachs Tokyo as the sole technologist of Tokyo's GSPS team, a principal strategies unit managing the firm's capital. In 2005, he changed careers to become a financial analyst with GSPS, and in 2007, he transferred to GSIP (Goldman Sachs Investment Partners) as part of the spin-out of the team into GSAM. As a financial/analyst and portfolio manager, Amin managed listed/unlisted equities, bonds, swaps, interest rate products, foreign exchange, derivatives as well as overall risk management. He was promoted to Managing Director in 2013 and retired from Goldman Sachs on December 31, 2017, to found cryptact. Gaku Saito, Co-CEO Having completed a Bachelor's degree in System Innovation Engineering in 2005 and a Master's degree in Environmental & Ocean Engineering in 2007 from The University of Tokyo, Gaku joined Goldman Sachs – Asia Special Situations Group, where he executed investments exceeding US$500 million in non-performing and sub-performing loan portfolios, private equity, real estate portfolios, and vessel portfolios. Also, he participated in a number of sponsorship auctions on bankrupt real estate developers. From May 2010 to January 2019, he worked at Goldman Sachs Investment Partners Worked as a portfolio manager at a multi-asset hedge fund, managing an US$800 million portfolio. His main investment strategy was equity long/short in listed companies based on a fundamental approach to building financial models. He also invested in equity derivatives, bond/CDS, FX, and mezzanine loan products. Since February 2019, he has been serving as Co-CEO of cryptact, and in 2021, he was appointed as Chairman of the JCBA Tax Review Department. About the Team Cryptact is developed and operated by a diverse, multinational team. With expertise in finance, technology and blockchain, the team brings a global perspective to deliver a trusted and efficient crypto tax service. https://www.pafin.com/en#team About pafin Inc. Services Cryptact - Crypto tax calculations: Simplified - Automatically calculate capital gains, access all the information you need for tax filing, and efficiently manage your portfolio -- all in one place. Trusted by over 150,000 active users. https://www.cryptact.com/en X account: https://x.com/CryptactGlobal defitact - Your Web3 Sidekick - defitact allows you visualize, analyze and manage your DeFi assets, NFTs and transactions through a highly intuitive and interactive interface. All features are for free. https://www.defitact.com/ Company Name: pafin Inc.Date Founded: January 2018Rep. Directors: Amin Azmoudeh, Co-CEO / Gaku Saito, Co-CEOEquity: 1,364M JPY (Including reserve)Location: Kojimachi HF Building 5F, Kojimachi 3-2-4, Chiyoda City, Tokyo, Japan 102-0083 Contact for public relations and media/press coverage-related inquiries pr@pafin.com
LONDON, Feb. 6, 2025 /PRNewswire/ -- Maybourne has today announced a 2027 opening for its newest development in the Parisian quarter of Saint-Germain-des-Prés, The Maybourne Saint-Germain, bringing a palace-style hotel with 101 keys and 23 ultra-luxury branded residences to Paris for the first time. The Maybourne Saint-Germain: Maybourne to bring palace-style hotel and ultra-luxurybranded residences to a historic landmark in Paris Expanding its prestigious hotel portfolio, Maybourne is creating an extraordinary property that reimagines bespoke hospitality in the City of Light, affirming its status as the eminent choice for global luxurians and strategically focusing on growth within select urban gateways. The Maybourne Saint-Germain is located along the Rive Gauche within the iconic 17th-century Îlot Saint-Germain, marking a new era for the historic building. The 23 residences will be envisioned by two renowned French interior designers, with seven by Pierre-Yves Rochon along Rue Saint-Dominque, and 16 residences by Laura Gonzalez, located on Rue de l'Université. In launching the first ever branded residences in Paris, Maybourne brings a unique offering to one of the world's most vibrant cities, continuing its legacy of fusing historical character with contemporary luxury and innovative hospitality. "Paris, with its elegance and timeless style, is an ideal match for Maybourne's vision of luxury hospitality," said Gianluca Muzzi, Co-CEO of Maybourne. "Our presence in this iconic city reflects our commitment to creating elevated experiences that celebrate the local culture and our brand's dedication to excellence. This opening marks an exciting step in our strategy to grow selectively in key urban gateways around the world, allowing us to build meaningful connections with our guests through rich and distinctive experiences." Positioned between Boulevard Saint-Germain and Rue Saint-Dominique, the Îlot Saint-Germain has been a Parisian landmark since the 17th century. Re-concepted for the 21st century, The Maybourne Saint-Germain will create a fourth era for Îlot Saint-Germain, seamlessly integrating with its heritage and creating a new layer of history. As with each of Maybourne's properties, The Maybourne Saint-Germain will be extraordinary in its own right while remaining connected to its sister hotels through the brand's signature craft, progressive vision, and unrivalled locations. The hotel will feature 50 suites and 51 rooms, surrounding a serene inner courtyard. Aspiring to be the living room of Saint-Germain, residents and guests will also have access to six food and beverage outlets, including a Japanese restaurant, patisserie, Salon de Thé, and more, and Maybourne's new wellness and longevity brand, Surrenne. A central part of the project, Surrenne will be one of Paris' largest luxury spa and health clubs offering immersive health, fitness, and beauty, as well as access to a third pool within the property. The 23 branded residences, all serviced by the hotel, will include access to a designated 25-metre pool accessible only by residents, in addition to the hotel's 30-metre rooftop pool (pictured above). This opening, born from a fusion of avant-garde Parisian chic with heritage and artistic flair, will mark Maybourne's first property in Paris and its second in France. To find out further information about The Maybourne Saint-Germain please visit maybourne.com/development. About Maybourne Maybourne operates some of the world's most storied and extraordinary bespoke hotels, including Claridge's, The Connaught, The Berkeley, The Emory, The Maybourne Beverly Hills and The Maybourne Riviera. Maybourne's purpose is to create stories of distinction that reflect the individual nature of its properties, its guests and its people, whilst maintaining a timeless and intuitive service style that are the hallmarks of its values.
Moove's total global fleet now comprises 36,000 vehicles. As part of its long term strategy to meet growing demand, Moove will order no fewer than 15,000 vehicles annually across all its markets. The acquisition strengthens Moove's ARR revenue to upwards of $275 Million (on a consolidated basis). Moove's presence now spans 19 cities across 6 continents, showcasing its scale and reach as a global mobility leader. This acquisition strengthens Moove's presence in LATAM, expanding its operational presence and economic impact in the region. Kovi's proprietary IoT software and driver behaviour algorithm will strengthen Moove's AI mobility strategy. DUBAI, UAE, Jan. 29, 2025 /PRNewswire/ -- Moove, a global leader in mobility with a vision to build the largest rideshare fleet and best-in-class technologies powering mobility platforms, has announced the acquisition of Kovi, an urban mobility provider headquartered in São Paulo. This strategic acquisition aligns with Moove's commitment to advancing mobility and expanding its footprint in the rapidly growing Latin American market. Launched in 2020, Moove has built the third side of mobility marketplaces by providing dedicated supply via Drive-to-Own, Taxi, and Autonomous fleets and continues to lead the transformation of mobility globally. The acquisition increases Moove's total global fleet to 36,000 vehicles and operations to 19 cities across 6 continents. It not only strengthens the company's position as one of the world's largest rideshare fleet operators, but incorporates Kovi's proprietary IoT software and advanced driver behaviour algorithm, which complement Moove's existing focus on safety and efficiency. These innovations will strengthen Moove's AI mobility strategy, further advancing its position as a global leader in mobility and autonomous vehicle innovation, while also reinforcing its commitment to driving economic growth in Latin America. Founded in 2018, Kovi has established itself as a pioneering force in making car ownership more accessible and efficient through innovative technology and financial solutions. With a robust fleet and a strong presence in Brazil and Mexico, Kovi has demonstrated impressive growth since inception. Its innovative approach to driver support and its strong foothold in Brazil bring significant value to Moove's global operations, strengthening its ability to expand into high growth markets and drive impactful change in mobility. Kovi's data-driven approach to vehicle management and user experience will complement Moove's existing capabilities, enabling the company to offer superior services to its customers. Ladi Delano, Co-Founder and Co-CEO of Moove, said: "Kovi has built an impressive business with a robust presence in Brazil, one of the most dynamic mobility markets in the world. We're thrilled to welcome them to the Moove family. This transaction not only strengthens our footprint in Latin America and reinforces our position as a dominant player in global mobility, but it also underscores our commitment to contributing to the Brazilian economy. Kovi's proprietary IoT software and advanced driver behaviour models complement our existing capabilities, supporting our focus on safety, efficiency, and innovation in AI mobility." Adhemar Milani Neto, CEO of Kovi, said: "Today, we stand at the forefront of a new era in mobility, and we believe that Moove has done a fantastic job at scaling their business on a global scale and with the right strategic angles. I met the founders many years back when they were scaling their business in Africa, and I was immediately impressed by their purpose-driven approach, which is also a perfect match to our culture. Together, I believe we will become a truly global category-defining business and will leverage scale and deep expertise never seen in our market. We are also excited to continue our expansion across Latam now with robustness with such strong partners." The completion of the transaction is subject to customary closing conditions, including approval from the Brazilian antitrust authority. About Moove Moove is building the world's largest fleet and best-in-class technologies that power mobility platforms. Its flagship Drive-to-Own (DTO) product democratises access to vehicle ownership with a revolutionary revenue based financing model, enabling underserved mobility entrepreneurs to thrive. Moove's growth has been fuelled by its global Uber partnership and support of leading investors and lenders, including Uber, Mubadala, BlackRock, MUFG, and many others. With operations now spanning 19 cities across 6 continents - Africa, Asia, Europe, North America, South America, and the Middle East - Moove continues to expand its offerings through strategic acquisitions and partnerships with industry leaders, including Waymo and Uber. Moove is transforming mobility to make it safer, more efficient and accessible to all, while providing economic opportunities and supporting skills development in the mobility sector. Key Facts Launched and scaled to 19 cities across 6 continents in 4 years, since 2020 launch Over 100,000 lives positively impacted through job creation and mobility access 36,000 vehicles in Moove's global fleet 50+ million trips completed in Moove-financed vehicles through its Uber partnership $500+ million in combined equity and debt funding raised from world-class investors including Uber, Mubadala, BlackRock, Franklin Templeton, Janus Henderson, and IFC (World Bank) Media Contact moove@zenogroup.com
倫敦2025年1月29日 /美通社/ -- IE International Education與MetaApply已簽署策略夥伴關係，將兩個品牌合併為一家公司，並將迅速成為國際高等教育和語言學習領域的重要市場參與者。 這兩個機構為有意出國留學的學生提供多項支援服務。 IE International Education/MetaApply將成為兩個品牌的全方位服務平台，結合最先進的人工智能技術來簡化流程，並結合實體存在以提供全球領先的成果。 該公司將採用共同行政總裁（Co-CEO）治理模式，任命Patrick Guimaraes為拉丁美洲和歐洲地區的行政總裁，並任命Prashant Sali為英國及世界其他地區的行政總裁。 負責拉丁美洲和歐洲地區的行政總裁Patrick Guimaraes表示，這次夥伴關係具有開創性。 Patrick Guimaraes表示：「結合這兩個機構的服務意味著學生現在可以獲得涵蓋所有學習需求的端到端服務。」 「這將是一項獨特的服務，將處於人生不同階段的人們與全球的教育機構和工作機會網絡連接起來。」 「這項夥伴關係對於擴大參與、促進社會流動性，並最終為全球盡可能多的學生創造更好的未來至關重要。」 負責英國及世界其他地區的行政總裁Prashant Sali表示，這筆交易將在國際教育領域帶來真正的變革。 Prashant Sali表示：「我們的新組織意味著學生可以直接與他們選擇的大學建立聯繫，同時還能透過同一服務解決他們的旅行、住宿和工作需求。」 「我們結合了人工智能技術，並在多個國際地點設有實體辦公室，意味著我們的服務隨時可用，滿足需求。」 「這項策略夥伴關係的重點是簡化服務，使更多人能夠實現國際學習，我們期待能夠幫助人們實現他們的教育和職業目標。」 如需有關MetaApply的更多資訊，請按此處。 如需有關IE International Education的更多資訊，請按此處。
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Co-CEO
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