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PASAY CITY, Philippines, Dec. 25, 2025 /PRNewswire/ -- SM Investments Corporation (SM Investments), the parent company of the SM group, has been certified as a Great Place to Work for 2025 by the global authority on workplace culture, Great Place to Work®. This certification is anchored on the Trust Index Survey, wherein SM employees affirmed long-term trust and satisfaction in the company. It also considers a Culture Brief that highlights SM's employee programs and workforce demographics. "We are grateful to be part of this list among Philippine companies. This recognition reaffirms our commitment to nurture a dynamic and inclusive environment for our employees who remain at the heart of our business. When our people thrive, business and communities thrive as well," said Frederic DyBuncio, President and Chief Executive Officer, SM Investments. Other SM companies also earned Great Place to Work® Certification this year, including SM Prime Holdings, Inc., SM Development Corporation, and SM Supermalls. With a workforce spanning generations, from Baby Boomers to Gen Z, Mr. DyBuncio said SM consciously cultivates a workplace where perspectives blend, mentorship opportunities flourish, and innovation is enriched by diversity. "Cross-generational teamwork has become a natural strength of our organization, creating a workplace that reflects the evolving society we serve," Mr. DyBuncio added. Globally, Great Place to Work® is the data scientist behind the Fortune 100 Best Companies to Work For™ list and other respected benchmarks, drawing insights from more than 100 million employees across 150 countries. About SM Investments Corporation SM Investments Corporation is one of the leading Philippine companies that is invested in market-leading businesses in retail, banking, and property. It also invests in ventures that capture high growth opportunities in the emerging Philippine economy. SM's retail operations are the country's largest and most diversified, consisting of grocery stores, department stores and specialty retail stores. SM's property arm, SM Prime Holdings, Inc., is the largest integrated property developer in the Philippines with interests in malls, residences, offices, hotels, and convention centers as well as tourism-related property developments. SM's interests in banking are in BDO Unibank, Inc., the country's largest bank, and China Banking Corporation, the fourth largest private domestic bank. For more information, please visit www.sminvestments.com
SYDNEY, Dec. 24, 2025 /PRNewswire/ -- Clarity Pharmaceuticals (ASX: CU6) ("Clarity" or "Company"), a clinical-stage radiopharmaceutical company with a mission to develop next-generation products that improve treatment outcomes for patients with cancer, is pleased to announce the acceptance of an abstract on the Co-PSMA (NCT06907641)[1] Investigator-Initiated Trial (IIT), led by Prof Louise Emmett at St Vincent's Hospital Sydney, for oral presentation at the upcoming European Association of Urology (EAU) Congress 2026, Europe's biggest urological conference, to be held 13-16 March 2026 in London, UK[2]. Co-PSMA's official study title is "Comparative performance of 64Copper [64Cu]-SAR-bisPSMA vs. 68Ga-PSMA-11 PET CT for the detection of prostate cancer recurrence in the setting of biochemical failure following radical prostatectomy". This Phase II IIT evaluated the performance of Clarity's diagnostic product, 64Cu-SAR-bisPSMA, in a head-to-head comparison to standard-of-care (SOC) 68Ga-PSMA-11 in 50 patients with low prostate-specific antigen (PSA) who were candidates for curative salvage therapy. Eligible patients were required to have had radical prostatectomy with no salvage therapy and a PSA level between 0.2 and 0.75 ng/mL. The results to be presented by Prof Emmett at the EAU Congress 2026 will expand on the earlier findings that the trial met its primary endpoint, demonstrating that 64Cu-SAR-bisPSMA positron emission tomography (PET) / computed tomography (CT) detected significantly more lesions per patient than the SOC, 68Ga-PSMA-11 PET/CT[3]. These results further build on the growing body of evidence showing that 64Cu-SAR-bisPSMA improves the detection of prostate cancer, compared to the current SOC prostate-specific membrane antigen (PSMA) PET agents which are known to have low sensitivity, especially in patients with low PSA levels[4],[5]. Clarity's Executive Chairperson, Dr Alan Taylor, commented, "64Cu-SAR-bisPSMA has been purposely developed at the benchtop to overcome the many shortfalls of the current SOC PSMA imaging agents. With the molecule only being invented some 7 years ago, we have already demonstrated at the cellular level, in animal models and now in multiple clinical trials, that 64Cu-SAR-bisPSMA is clearly differentiated from the competitors. In a very short amount of time, we have moved from invention to two registrational Phase III trials, both to complete recruitment next year, continuing to build on strong evidence generated to date of the improved diagnostic performance of our product through various clinical trials and real-world evidence (compassionate use supply). We reported earlier that our optimised agent detects more lesions in this IIT head-to-head comparison against the SOC product[3]. We also know that 64Cu-SAR-bisPSMA identifies more as well as smaller lesions and was able to do so earlier than SOC PSMA PET agents in our Phase II COBRA trial[6]. The full results from Co-PSMA will again reinforce the mounting data showing how 64Cu-SAR-bisPSMA can outperform SOC PSMA PET products. "We are committed to a rigorous scientific and clinical development process, which has delivered exceptional results to date. The acceptance of the Co-PSMA data by this world-leading urology conference for an oral presentation is a testament to its strength and quality. This recognition not only highlights the impact of this research but also underscores the significant potential of 64Cu-SAR-bisPSMA to advance PSMA imaging and improve prostate cancer management. The abstract summary will be announced in mid-February, followed by the oral presentation in mid-March 2026. "Prof Emmett is a global key opinion leader in the field of urologic nuclear medicine, with a strong track record of highly regarded scientific publications as well as extensive clinical experience. We are honoured to continue working together on our registrational AMPLIFY[7] and CLARIFY[8] trials and trust that her unique expertise and commitment to providing the best available patient care will help us to get closer to our mutual goal of improving detection and treatment paradigm for prostate cancer patients. "With two US Food and Drug Administration (FDA) Fast Track Designations for 64Cu-SAR-bisPSMA and two ongoing registrational trials, we are extremely excited to enter the USD 2 billion PSMA PET imaging market as it is further expected to grow to over USD 3 billion by 2029 with not only a clearly differentiated agent, but also a product with substantial logistical benefits over the current competitors." About SAR-bisPSMA SAR-bisPSMA derives its name from the word "bis", which reflects a novel approach of connecting two PSMA-targeting agents to Clarity's proprietary sarcophagine (SAR) technology that securely holds copper isotopes inside a cage-like structure, called a chelator. Unlike other commercially available chelators, the SAR technology prevents copper leakage into the body. SAR-bisPSMA is a Targeted Copper Theranostic that can be used with isotopes of copper-64 (Cu-64 or 64Cu) for imaging and copper-67 (Cu-67 or 67Cu) for therapy. Disclaimer 64Cu-SAR-bisPSMA is an unregistered product. The safety and efficacy of 64Cu-SAR-bisPSMA have not been assessed by health authorities such as the US FDA or the Therapeutic Goods Administration (TGA). There is no guarantee that this product will become commercially available. About Prostate Cancer Prostate cancer is the second most common cancer diagnosed in men globally and the fifth leading cause of cancer death in men worldwide[9]. Prostate cancer is the second-leading causes of cancer death in American men. The American Cancer Institute estimates in 2025 there will be about 313,780 new cases of prostate cancer in the US and around 35,770 deaths from the disease[10]. About Clarity Pharmaceuticals Clarity is a clinical stage radiopharmaceutical company focused on the treatment of serious diseases. The Company is a leader in innovative radiopharmaceuticals, developing Targeted Copper Theranostics based on its SAR Technology Platform for the treatment of cancers. www.claritypharmaceuticals.com For more information, please contact: Clarity Pharmaceuticals Dr Alan Taylor Lisa Sadetskaya Executive Chairperson Director, Corporate Communications ataylor@claritypharm.com lisa@claritypharm.com References [1] Clinicaltrials.gov Identifier: NCT06907641. https://clinicaltrials.gov/study/NCT06907641 [2] EAU26. The Congress. https://eaucongress-new.uroweb.org/the-congress [3] Clarity Pharmaceuticals. Co-PSMA trial achieves primary endpoint. https://www.claritypharmaceuticals.com/news/co-psma-endpoint/. [4] Fendler WP et al. Assessment of 68Ga-PSMA-11 PET Accuracy in Localizing Recurrent Prostate Cancer: A Prospective Single-Arm Clinical Trial. JAMA Oncol. 2019 Jun 1;5(6):856-863. doi: 10.1001/jamaoncol.2019.0096. PMID: 30920593; PMCID: PMC6567829. [5] Mena E, Lindenberg ML, Turkbey IB, Shih JH, Harmon SA, Lim I, Lin F, Adler S, Eclarinal P, McKinney YL, Citrin D, Dahut W, Wood BJ, Krishnasamy V, Chang R, Levy E, Merino M, Pinto P, Eary JF, Choyke PL. 18F-DCFPyL PET/CT Imaging in Patients with Biochemically Recurrent Prostate Cancer After Primary Local Therapy. J Nucl Med. 2020 Jun;61(6):881-889. doi: 10.2967/jnumed.119.234799. Epub 2019 Nov 1. PMID: 31676732; PMCID: PMC9374042. [6] Nordquist et al. COBRA: Assessment of safety and efficacy of 64Cu-SAR-bisPSMA in patients with biochemical recurrence of prostate cancer following definitive therapy. EANM 2024. [7] Clinicaltrials.gov Identifier: NCT06970847. https://clinicaltrials.gov/study/NCT06970847 [8] Clinicaltrials.gov Identifier: NCT06056830. https://clinicaltrials.gov/study/ NCT06056830 [9] Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. https://acsjournals.onlinelibrary.wiley.com/doi/10.3322/caac.21660 [10] American Cancer Society: Key Statistics for Prostate Cancer. https://www.cancer.org/cancer/prostate-cancer/about/key-statistics.html This announcement has been authorised for release by the Executive Chairperson.
VIENNA, Dec. 24, 2025 /PRNewswire/ -- Bybit EU, the European arm of Bybit and a MiCAR-licensed crypto-asset service provider headquartered in Vienna, is commemorating Bybit's Seventh Anniversary with the launch of its EU-only #7UpBybit Birthday Blast, featuring a special reward in partnership with ZEN.COM. Eligible EU participants may redeem 150 days of complimentary access to the ZEN PRO plan, valued at €34.50, through activities available exclusively to users on the Bybit EU platform. This reward is part of the Bybit EU Daily Treasure Hunt, which runs from Nov. 26, 2025, at 10 a.m. UTC to Jan. 5, 2026, at 10 a.m. UTC. Only Bybit EU users participating in the EU anniversary campaign are able to earn and redeem Bybit Points for this benefit. How It Works The reward may be redeemed once per eligible EU user. Users must be opening a ZEN.COM account for the first time in order to activate the ZEN PRO plan. After redeeming the reward with Bybit Points on the EU platform, users will receive a unique reward code from Bybit EU for use with their new ZEN.COM account. If the reward is redeemed by someone who is not new to ZEN.COM, the reward will be unusable and Bybit Points will not be refunded. Throughout the anniversary period, only users on the Bybit EU platform can participate in tasks that earn Bybit Points, including daily check-ins, account verification with first top-up, daily spot trading, and referral activities conducted within the EU ecosystem. Points may be redeemed across EU-only anniversary features, including USDC airdrops, fee savers, and 100,000 scratch cards available on a first-come, first-served basis. T&Cs apply. More information on the EU campaign is available here. Bybit Marks Seventh Anniversary With Exclusive EU-Only ZEN.COM PRO Plan Reward #BybitEU / #TheCryptoHub About Bybit EU Bybit EU GmbH is an Austrian company that serves customers across the entire European Economic Area (EEA*) – with the exception of Malta – via the platform Bybit.eu. Operated by Bybit EU GmbH, a licensed Crypto-Asset Service Provider (CASP) under the Markets in Crypto-Assets Regulation (MiCAR), Bybit EU delivers fully regulated services, including crypto custody, exchange, and rewards products and more, in full compliance with European regulations for investor protection and market integrity. Bybit EU GmbH is a licensed Crypto-Asset-Service Provider under the Markets in Crypto Assets Regulation (MiCAR), authorized to offer the following services to residents of the European Economic Area (except Malta): providing custody and administration of crypto-assets on behalf of clients; exchange of crypto-assets for funds; exchange of crypto-assets for other crypto-assets; placing of crypto-assets; and providing transfer services for crypto-assets on behalf of clients. Bybit EU GmbH is neither the operator of a trading platform for crypto-assets nor provides investment advice. Media Contact: press@bybit.comwww.bybit.eu Disclaimer: This press release is provided for informational purposes only and does not constitute investment advice or an offer to buy or sell digital assets. The products and services mentioned herein are subject to applicable laws and regulations in the relevant jurisdictions and may not be available in certain regions.
PANAMA CITY, Dec. 23, 2025 /PRNewswire/ -- HTX Ventures, the global investment arm of HTX, has released a new research report titled Pulse in the Cold: How x402 and ERC-8004 Signal Web3's Next Technical Inflection Point. The report examines two emerging but often overlooked infrastructure upgrades—x402 and ERC-8004—and analyzes how they could reshape Web3's payment, identity, and coordination layers as machines increasingly become primary network users. HTX Ventures points out that periods of cooling market sentiment have historically coincided with the quiet formation of technologies that later define the industry's next growth phase. In the current cycle, as price-driven narratives lose momentum, x402 and ERC-8004 stand out as structurally significant signals pointing to a deeper transformation underway. It's worth noting that the technical developments of machine economy have caught the attention of the industry leaders. HTX has actively tracked advances in AI agent–driven and machine-economy–oriented infrastructure this year, and has already listed projects associated with the x402 sector, including PING and PAYAI. These listings provide users with early exposure to technologies that may underpin future machine-native markets. Machines Are Becoming the Internet's New Primary Users The report places today's market environment in a broader historical context. From NFTs and DeFi to rollups, many of Web3's most consequential infrastructure developments took shape during downturns, when attention shifted away from price action and toward underlying capabilities. HTX Ventures observes that a similar pattern is emerging today, driven by a fundamental change in who—or what—uses the internet. Automation scripts, API-based services, AI agents, and model inference systems are rapidly increasing their share of global network activity. Unlike human users, these machine users do not rely on interfaces or subjective decision-making. Instead, they operate at high frequency, require fully automated execution, and depend on programmable, verifiable settlement. This shift places new demands on infrastructure. Traditional Web2 systems, built around human workflows, account-based access, and centralized trust, struggle to support large-scale, machine-to-machine interaction. By contrast, Web3's native properties—programmable payments, on-chain identity, and verifiable execution—are structurally aligned with the needs of machine-driven activity. x402 and ERC-8004: A Minimal Infrastructure Stack for the Machine Economy HTX Ventures argues that x402 and ERC-8004 should not be viewed as isolated proposals, but as complementary responses to a single question: how machines can participate in economic activity. x402 redefines how payment functions on the internet. By reviving the long-dormant HTTP 402 ("Payment Required") status code, x402 turns payment into a protocol-level semantic rather than a user-interface flow. A server can directly specify payment conditions, while a calling machine can autonomously complete the payment—typically via stablecoins—and proceed with execution. In this model, payment becomes machine-readable, machine-executable, and scalable, positioning stablecoins as a natural form of "machine money." ERC-8004 addresses the problem of trust and cooperation between machines. In a world where software agents can be copied or replaced at will, the default state is not weak trust, but zero trust. ERC-8004 introduces a standardized framework for task description and execution proofs, allowing agent behavior to be recorded, verified, and tracked on-chain. Over time, these records form a data-driven reputation, enabling collaboration based on verifiable history rather than implicit trust. At a higher level, the report frames x402 and ERC-8004 as forming a minimal closed loop for the machine economy: payment, execution, verification, reputation, and cooperation. Within this loop, machines evolve from passive tools into active economic participants capable of initiating requests, bearing responsibility, and accumulating track records. Conclusion HTX Ventures concludes that major technical inflection points rarely coincide with immediate market feedback. Instead, they emerge gradually at the structural level. As machines increasingly become the internet's dominant users, Web3's role is likely to shift—from a human-facing interaction layer to a foundational system for machine payment, execution, and trust. In this transition, x402 and ERC-8004 may not immediately dominate headlines, but they could become enduring components of future automated systems, forming a critical foundation for Web3's next phase of technical evolution. About HTX Ventures HTX Ventures is the global investment arm of HTX, integrating investment, incubation, and research to identify and discover the best and most innovative projects in the market. Visit us here.
PASAY CITY, Philippines, Dec. 23, 2025 /PRNewswire/ -- SM Investments Corporation (SM Investments), in partnership with the Global Reporting Initiative (GRI), has launched the inaugural e-learning bridge course on sustainability reporting for micro, small, and medium enterprises (MSMEs). The course was unveiled during a recently concluded training workshop for publicly listed companies (PLCs) at SMX Aura in Taguig. The event, "Empowering Sustainable Business and Supply Chains: Building Capabilities for Impactful Sustainability Practices Across the Value Chain," aimed to help PLCs understand the interoperability between GRI Standards and the emerging disclosure expectations of the International Sustainability Standards Board (ISSB). "It's not just about producing reports and documentation," said SM Investments Consultant and Head of Investor Relations and Sustainability Timothy Daniels. "We want to deepen understanding beyond the stories and behind the data, to empower our colleagues in the industry and now our MSME partners to create real business value." MSMEs represent about 99.5% of operating businesses in the Philippines, and the SM Group works with more than 100,000 MSMEs across its value chain. To help these enterprises become catalysts for sustainable change, SM and GRI co-developed a free bridge course to build foundational sustainability and reporting knowledge among MSME owners, suppliers, and partners. SM Investments will sponsor the free, self-paced online course, while GRI will facilitate dissemination through its platform partners. The course will also be shared across SM's MSME network. Participants will gain foundational knowledge of key sustainability and climate-related concepts, understand the benefits of sustainability reporting, and receive practical guidance on how to begin implementing these practices within their operations. As sustainability reporting becomes both a responsible business decision and a strategic advantage, SM Investments continues to strengthen its partnership with GRI, which began in 2018. "When we first introduced GRI in the Philippines, who helped us? It was SM," said Dr. Allinnettes Go Adigue, Head of the ASEAN Regional Hub of GRI. "They supported us in spreading the word. Within a few years, compliance grew rapidly. With committed partners from the private sector, we can continue supporting your sustainability journey." What began as an initiative to strengthen SM's own sustainability reporting has evolved into a long-term partnership that has helped elevate sustainability practices in the Philippines. GRI's first Sustainability Summit outside Europe and North America was held in 2018 co-hosted with SM. "Our success as a group is deeply connected to the success of our stakeholders, especially the MSMEs who work with us and rely on us," added Mr. Daniels. "Through capability-building programs like this, we extend sustainability beyond our organization, helping ensure it becomes a shared practice across industries." About SM Investments Corporation SM Investments Corporation is one of the leading Philippine companies that is invested in market-leading businesses in retail, banking, and property. It also invests in ventures that capture high growth opportunities in the emerging Philippine economy. SM's retail operations are the country's largest and most diversified, consisting of grocery stores, department stores and specialty retail stores. SM's property arm, SM Prime Holdings, Inc., is the largest integrated property developer in the Philippines with interests in malls, residences, offices, hotels, and convention centers as well as tourism-related property developments. SM's interests in banking are in BDO Unibank, Inc., the country's largest bank, and China Banking Corporation, the fourth largest private domestic bank. For more information, please visit www.sminvestments.com
The accolade marks another major milestone for the reimagined Dusit Thani BangkokBANGKOK, THAILAND - Media OutReach Newswire - 22 December 2025 - Cannubi by Umberto Bombana at Dusit International's reimagined flagship hotel, Dusit Thani Bangkok, has been awarded One Michelin Star in The Michelin Guide Thailand 2026 – the first time an Italian restaurant in Thailand has received the distinction. Curated by renowned chef Umberto Bombana (right), Cannubi by Umberto Bombana at Dusit Thani Bangkok has made history as the first Italian restaurant in Thailand to receive one Michelin star. His vision is brought to life in Bangkok by Executive Italian Chef Andrea Susto (left). Curated by the renowned Chef Umberto Bombana – best known for his Hong Kong flagship, 8½ Otto e Mezzo Bombana, the world's only three-Michelin-starred Italian restaurant outside Italy – Cannubi by Umberto Bombana reflects the chef's lifelong dedication to exceptional produce, terroir, and refined Italian cooking. His philosophy is brought to life in Bangkok by his longtime protégé, Executive Italian Chef Andrea Susto, who works with the finest locally sourced and imported ingredients to craft classically rooted dishes refined with contemporary technique. Seasonal à la carte offerings, tasting menus, a set lunch experience, and a celebrated white truffle menu – honouring Bombana's reputation as The King of White Truffles – are complemented by a thoughtfully curated wine list of more than 350 labels chosen for their heritage, character, and quality. Cannubi by Umberto Bombana's design plays an equal role in shaping the dining experience. Situated on the lobby level of the reimagined Dusit Thani Bangkok, the two-level space looks out over the hotel's dramatic nine-storey waterfall. Inside, the main dining room is crowned with intricately carved golden teakwood panels preserved and meticulously restored from the original hotel's Benjarong restaurant. These heritage teak elements, combined with flowing lines and atmospheric lighting, create a warmly intimate setting, complemented by private dining rooms accommodating six and twelve guests. "To be recognised as the first Italian restaurant in Thailand to receive a Michelin Star is a tremendous honour," said Chef Umberto Bombana. "Cannubi by Umberto Bombana is a project very close to my heart, created to express the truth and soul of Italian cuisine through integrity, passion, and respect for exceptional ingredients. Seeing this spirit recognised in Bangkok means the world to me. I am incredibly proud of Chef Andrea Susto and our entire team. This accolade also reflects the vision of the new Dusit Thani Bangkok, where craftsmanship and creativity shape every detail." Cannubi by Umberto Bombana's Michelin Star adds to a remarkable year for Dusit Thani Bangkok, which, since reopening in September 2024, has received one Michelin Key and earned its place among the world's top 100 hotels, ranking #60 on the inaugural extended list of The World's 50 Best Hotels 2025. The restaurant's achievement further strengthens the hotel's emergence as one of the region's most compelling new dining destinations, with Pavilion, Dusit Gourmet, 1970 Bar, and the dramatic rooftop venue, Spire Rooftop Bar, among the other standout options. Cannubi by Umberto Bombana is open for lunch and dinner from Tuesday to Sunday. For more information, please visit dusit.com/dusitthani-bangkok. Hashtag: #DusitHotelsThe issuer is solely responsible for the content of this announcement.About Dusit Thani Bangkok Part of the landmark Dusit Central Park development, Dusit Thani Bangkok is a reimagined icon that blends timeless Thai elegance with contemporary sophistication. With a prime location overlooking Lumpini Park in the heart of the city, the 257-key property redefines luxury with all park-view accommodations and sets the scene for unforgettable experiences with world-class dining and peerless event venues. More than just a hotel, Dusit Thani Bangkok brings classic grandeur to life and invites discerning travellers to experience a vibrant blend of modern elegance and timeless charm inspired by the original hotel's rich heritage and Dusit's unique brand of gracious Thai hospitality. For more information, please visit dusit.com/dusitthani-bangkokAbout Dusit Hotels and Resorts Dusit Hotels and Resorts is the hotel arm of Dusit International, one of Thailand's leading hotel and property development companies. With a heartfelt belief and commitment to introducing Thai-inspired gracious hospitality to the world, Dusit Hotels and Resorts offers guests a uniquely special stay in high-style surroundings and a personalised approach to service. The group's portfolio of hotels, resorts and luxury villas includes close to 300 properties operating under a total of nine brands (Devarana – Dusit Retreats, Dusit Thani, Dusit Suites, Dusit Collection, Dusit Hotels, dusitD2, Dusit Princess, ASAI Hotels, and Elite Havens) across 18 countries worldwide. For more information, please visit dusit.com
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