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In the preliminary findings of a study conducted with the National Taiwan University Hospital, over 50% of sample cases were reclassified as HER2-expressing when 3D pathology was applied. HSINCHU, April 17, 2025 /PRNewswire/ -- JelloX Biotech Inc., a Taiwan-based startup at the forefront of cancer pathology, announced the preliminary results of a research collaboration with the National Taiwan University Hospital (NTUH) on breast cancer patients. The study found that JelloX's 3D pathology technology identified a significantly increased proportion of tumors with HER2-low and HER2-ultralow expression compared to conventional methods, demonstrating this technology's increased sensitivity and potential as a superior diagnostic tool for HER2 detection in breast cancers. This is a 3D fluorescent-stained image of mammary ducts from a breast cancer patient. Green areas indicate drug-targeted receptors. Unlike traditional 2D pathology, this reveals the spatial distribution of receptors, reducing the risk of misjudging treatment decisions. Contact JelloX at sales@jellox.com to explore partnerships and learn more about the company's cutting-edge 3D pathology technology. According to the US National Cancer Institute, breast cancer is the most prevalent form of cancer. However, the difficulty of precisely determining treatment has made the identification of HER2 expression essential. In HER2-low and HER2-ultralow metastatic breast cancer, the novel antibody-drug conjugate (ADC) Trastuzumab deruxtecan (T-DXd) has demonstrated robust efficacy over conventional chemotherapy. Yet considering HER2 spatial heterogeneity, traditional diagnostic methods have shown to be less precise than 3D pathology in detecting the presence of the HER2 protein. "For the specific challenges posed by metastatic breast cancer and the need to identify predictive biomarkers accurately, the high sampling capacity of 3D pathology holds particular potential," commented Dr. Yen-Yin Lin, CEO of JelloX. "JelloX Biotech's Comprehensive HER2 Diagnostic Solution is poised to revolutionize HER2 diagnostics. With a more comprehensive data set on tumor samples, healthcare providers can be empowered to make more precise diagnoses, ensuring that the right patients receive the right treatment at the right time." New findings with NTUH on HER2 breast cancer In JelloX's research collaboration with NTUH, preliminary findings indicate that more than half of the analyzed cases exhibited diagnostic discrepancies when re-evaluated using the company's advanced 3D pathology methods. Notably, among patients initially classified as HER2-null by traditional methods, more than 66.7% were reclassified as HER2-expressing (HER2-low or HER2-ultralow) using 3D technology, thereby becoming potentially eligible for T-DXd treatment. These findings echo the company's recent results using samples from colorectal and esophageal cancers, demonstrating that 3D pathology may have broader potential across various cancer types. The full findings will be shared at the Global Breast Cancer Conference in South Korea on April 17. https://gbcc.kr/Main.asp Implications for breast cancer treatment and drug guidelines T-DXd has demonstrated significant efficacy in tumors with HER2 expression. However, tumors classified as HER2-null under conventional pathological testing are ineligible for T-DXd treatment. By detecting HER2 more precisely using 3D pathology methods, we can identify more patients eligible for T-DXd therapy. In addition to cancer patients, JelloX's 3D pathology technology has the potential to expand possibilities across healthcare stakeholders: For physicians: This advanced diagnostic tool offers a more comprehensive patient data set and, when integrated with AI, helps reduce physician workloads. For pharmaceutical companies and research institutions: The technology enhances companion diagnostics (CDx) for drug usage and is a valuable tool for new drug development. For healthcare systems: 3D pathology optimizes medical resource allocation and minimizes unnecessary financial and healthcare burdens. About JelloX Biotech Inc. Based in Hsinchu, Taiwan, JelloX Biotech Inc. is a startup that focuses on advancing cancer pathology through 3D digital imaging and AI technology. For more information, please visit: https://jellox.com/en/home/
Milan, Italy - April 11, 2025 - (SeaPRwire) - Zakeke, a leading Visual Commerce platform, proudly announces the launch of its new 3D Digital Asset Manager. This powerful platform enhances Zakeke's suite by enabling the creation, storage, and management of 3D models and catalogs - without high costs or long wait times. The platform makes 3D more accessible, even for small brands, while Zakeke aims to democratize immersive technologies across various industries, including fashion, furniture, jewellery, and sports equipment. The 3D Digital Asset Manager addresses a critical need in the e-commerce sector by offering a comprehensive suite of tools that simplify the creation, storage, and sharing of 3D models. With its advanced technology, businesses can effortlessly convert 2D images into 3D models without needing a 3D artist, eliminating costly photoshoots and physical samples. This streamlines workflows and reduces waste, making it a more sustainable solution by minimizing the need for excess inventory and physical prototypes. The platform integrates seamlessly with e-commerce platforms, allowing businesses to showcase hundreds of product variants in seconds without requiring extensive IT expertise. CEO Angelo Coletta emphasizes the importance of this launch, stating, "Our 3D Digital Asset Manager will transform how companies approach product visualization and customer interaction. The streamlined creation and management of 3D assets lets businesses focus on what matters most—enhancing customer experience and driving sales. Furthermore, the accessibility of 3D to all empowers small brands to compete effectively with larger enterprises." Improving Operational Efficiency and Customer Engagement The 3D Digital Asset Manager creates operational efficiency by providing a centralized hub for managing all 3D assets. This eliminates file chaos and allows businesses to collaborate on 3D models more effectively. Teams work together seamlessly, managing permissions and aligning all stakeholders in their marketing efforts. Additionally, the platform offers performance analysis tools, enabling businesses to track 3D model interactions and refine their marketing strategies based on real-time data. The global e-commerce market continued to grow throughout 2024, emphasizing immersive shopping experiences. Consumers now expect interactive and engaging content, which drives the demand for 3D digital assets. Zakeke's solution meets this demand by providing businesses with tools to create dynamic marketing materials, such as automated 360° GIFs and videos, greatly enhancing audience engagement. The platform supports no-code 3D model sharing, allowing businesses to share their assets instantly via links or QR codes. This feature enables companies to spread their 3D content across various digital platforms, further amplifying their brand presence and customer interaction. Real-World Applications and Future Prospects In real-world applications, Zakeke's 3D Digital Asset Manager demonstrates substantial potential across various sectors. Fashion brands now showcase hundreds of styles in 3D, reducing the need for physical samples and photoshoots. Meanwhile, furniture companies manage numerous 3D models with ease, optimizing their operational efficiency. Sports brands utilize the platform to create engaging marketing materials for limited-edition gear, enhancing their merchandising strategies. Businesses can integrate Zakeke's 3D Digital Asset Manager into their e-commerce infrastructure with minimal setup required. Subsequently, this seamless integration ensures that companies quickly start creating, managing, and sharing 3D models without extensive technical expertise. Angelo Coletta concludes, "Looking toward the future, we believe that our 3D Digital Asset Manager will play a pivotal role in shaping the e-commerce landscape. Empowering businesses of all sizes to harness the power of 3D enhances product visualization while opening new avenues for customer engagement and brand storytelling." Visit Zakeke's Website to learn more about the 3D Digital Asset Manager and how it can transform your business operations. About Zakeke Zakeke pioneers visual commerce solutions, offering a comprehensive suite of tools designed to enhance the online shopping experience. With a focus on advancement and user-friendly technology, Zakeke serves thousands of businesses across various industries, helping them stay at the forefront of e-commerce trends. The company positions itself as a leader in the field through its dedication to advancing visual commerce technology, continuously pushing the boundaries of what's possible in online retail. Contact Information Contact: Alessia Dozzo Brand: Zakeke Website: https://www.zakeke.com Email: a.dozzo@zakeke.com
DETROIT, April 10, 2025 /PRNewswire/ -- Creality, a leading global 3D printing technology brand, celebrated its 11th anniversary at the Renaissance Center of Detroit by the announcement of new products and an updated visual identity. The celebration was held with creators to showcase their creative 3D printing projects that are contributing to everyday life. Updated Visual Identity Creality has always dedicated itself to taking an extra step in supporting innovation. Now with a comprehensive product portfolio that meets all 3D printing needs, the brand has updated its visual identity to match. Creality adopts an original font and a new mascot Maker—which stands for Multi-functional Adaptive Knowledge 3D Engineering Robot—to better reflect its brand innovation. In addition to enhancing the brand's recognition, Maker will serve as a technical instructor for all 3D printing lovers. These visuals will be rolled out across all company materials, product packaging, and branding assets over time. Creality's new mascot Maker—stands for Multi-functional Adaptive Knowledge 3D Engineering Robot. Unleashing Creativity Following the spirit of the ShareFest, an event series celebrating creativity nurtured by 3D printing, Creality's anniversary event also had the honor to provide an opportunity for real makers to elaborate how 3D printers make their unique ideas sparkle. Sterling Backus, a physicist known for his 3D-printed Lamborghini Aventador, shared his 5-year experiment on the car; he also envisioned 3D printing in broader industrial applications. Purdue University's Rick Womack explained how higher-education students can benefit from Creality's accessible printers in his 3D Printing Club, and the educational value of 3D printing technology. Veteran 3D printing user Ian Davis has been in the field of engineering for three decades. As a cancer survivor, Ian designed and produced his own prosthetic hand, and actively customized 3D-printed devices for others. YouTuber SaturdayMorningProps's Dylan O'Connell shared the experience of reliving his childhood dreams about classic sci-fi movies through his 3D-printed props. "We are thrilled to see so many creative minds realizing their dream projects with the help of Creality products," said Michael Tang, Chief Technology Officer of Creality, "Their creations are truly inspiring and drive us to push the boundaries of what's possible. Whether in the past or the future, Creality remains committed to expanding the possibilities of 3D printing, empowering both professionals and hobbyists to turn their visions into reality." Expanding Product Ecosystem At the event, Creality unveiled its K2 & K2 Pro, further expanding its K2 Series—flagship FFF (fused filament fabrication) large-format multi-color 3D printers. These models join the popular K2 Plus, reinforcing a strong mid-to-high-end product range designed for exceptional performance and versatility. Together with the Creality RaptorX 3D scanner, the K2 series won the Red Dot Design Award 2025 in the Industrial Equipment, Machinery, and Automation category—a testament to its unparalleled innovation in industrial-grade 3D printing solutions. Unlike traditional stepper motors that often lose steps under load, the K2 series features FOC step-servo motors, ensuring high accuracy by providing precise control over position and speed, along with improved thermal performance. The printers boast a unibody die-cast frame design, which simplifies the structure while enhancing product consistency and durability. The Creality ecosystem is a powerhouse of innovation. From the Falcon A1 Pro laser engraver and Otter Lite 3D scanner, SpacePi X4 filament dryer, to the HALOT-X1 resin 3D printer and Soleyin Filament, each product works seamlessly together to drive technological advancement and to elevate the 3D printing experience. Emil Ma, Head of Branding and Marketing, remarked at the event: "Creality carefully listens to users feedback and continues to evolve—from the self-developed step-servo motor to AI features in the latest CrealityCloud 6.0, Creality makes breakthroughs that really respond to what the community needs." About Creality Founded in Shenzhen in 2014, Creality is a global pioneer in the 3d printing industry that focuses on the research, design and production of consumer and professional-grade 3D printers and 3D printing accessories. As a user-centric company, Creality has expanded its footprint across more than 100 countries and regions and shipped over 5 million 3D printers worldwide, introducing 3D printing to homes, schools, workshops, factories and academic institutions, and driving digitalization in manufacturing, education, healthcare, architecture and beyond.
HONG KONG, April 9, 2025 /PRNewswire/ -- XGRIDS LIMITED has officially launched the commercial release of brand new Lixel CyberColor Solution (LCC), following extensive beta testing with industry partners. This enterprise-grade solution combines 3D Gaussian Splatting with multi-SLAM technology to transform spatial data capture, processing, and utilization across multiple industries.   LCC enables organizations to create measurable, interactive, and photorealistic 3D models and digital twins by integrating LiDAR and visual data from Lixel series scanners. These digital environments provide actionable spatial intelligence for improved decision-making and visualization. "With LCC Studio, we're democratizing access to advanced spatial computing tools that were previously available only to specialized technical teams," said Kaiyong Zhao, CEO of XGRIDS. The platform offers tailored solutions for eight key verticals: Architecture & Construction: Detailed as-built documentation with precise measurement capabilities Real Estate: Immersive virtual property tours with interactive notes and seamless space transitions Industrial Digitization: Comprehensive digital twins for operational efficiency Facility Inspection: Detailed documentation for maintenance planning and compliance Robotics & Embodied AI: Spatial intelligence for navigation and environment recognition Cultural Heritage: High-fidelity preservation and virtual access to historical sites Entertainment & Gaming: Realistic environmental assets for production Education: Immersive learning environments with spatial context Key Technical Advancements: Rapid Processing: Converts 10 minutes of scanning into detailed 3D models in approximately 100 minutes. Efficient Storage: File sizes up to 88% smaller than traditional methods. Enhanced Accuracy: Advanced measurement tools provide precise spatial data. Map Fusion: Seamless integration of aerial and ground scans into cohesive models. Easy Publishing: Cloud-based management with custom URLs and controlled access. LCC is available in two tiers: Basic Version with core functionality Premium Version with advanced pro features "Our pricing structure enables both small studios and large enterprises to leverage this technology for competitive advantage," explained Sunny Liao, Director of Global Sales at XGRIDS. All versions are available immediately through XGRIDS' global distribution network.For inquiries: enterprise@xgrids.com About XGRIDS XGRIDS is a global leader in SLAM-based 3D scanning and 3D Gaussian Splatting technology, providing solutions for virtual production, architecture, engineering, construction, gaming, and digital twins. The company's Lixel series scanners and LCC 3D reconstruction technology deliver high-accuracy, measurable 3D models that transform workflows across industries.
DETROIT, April 8, 2025 /PRNewswire/ -- Elegoo, a rapidly developing brand in global smart manufacturing, announces the debut of its Jupiter 2 large-format resin 3D printer at RAPID+TCT 2025. Featuring an all-new double-door design distinct from previous Jupiter models, it aims to push the boundaries of resin 3D printing technology, enabling hobbyists and professionals to bring their big ideas to life with smart and precise engineering. "The Jupiter 2 is our bold step forward in elevating the resin 3D printing experience," says Chris Hong, CEO of Elegoo. "We're setting a new industry benchmark by delivering a reliable, high-efficiency printer capable of handling demanding projects with consistent results." Elegoo debuts Jupiter 2, a large-format resin 3D printer for bigger ideas and smarter engineering, at RAPID + TCT 2025. Next-gen tech and design for pro-level resin printing The Jupiter 2 features an expansive build volume of 302.40 x 161.98 x 300.00 mm, the largest in the Jupiter series, ideal for large-scale projects. It raises the bar with a 14-inch 16K LCD screen, achieving the series' highest 20×26µm XY resolution for razor-sharp details and ultra-smooth surfaces. A fully enclosed light source ensures flawless prints, while multi-point auto-leveling guarantees precise calibration with minimal effort. For advanced users, a manual leveling option offers additional control. Enhanced efficiency with modular design and resin management system The Jupiter 2 prioritizes efficiency with its modular design, allowing users to swap the LCD screen in 10 minutes, five times faster than traditional setups. Replacing the release film takes just 10 seconds, 10 times faster than conventional methods. The Jupiter 2 also introduces a smart resin management system, automatically feeding and recycling resin with a detachable box that can hold a 2kg resin bottle. This smart system allows users to focus on their designs rather than constantly monitoring resin levels. The heated resin tank ensures that the resin stays at the ideal temperature, guaranteeing consistent results throughout the print process. Smarter monitoring for reliable results Users can monitor prints remotely via the built-in camera, with adaptive lighting for clear visibility in any environment. Automatic overheat alerts enhance safety, while integration with Elegoo's SatelLite resin slicer enables seamless device control and production optimization. Availability and applications The Jupiter 2, launching in Q3 2025, is expected to have broad applications in toys, healthcare, consumer goods, and prototyping. Compatibility with engineering resins further expands its versatility. More exciting features will be revealed soon. In addition to the Jupiter 2, Elegoo showcases its latest product lineup at the event, including the award-winning Centauri Carbon, Saturn 4 Ultra 16K, OrangeStorm Giga, and Mercury Plus V3.0. For more information, please visit Elegoo official website and its social media platforms, including Facebook, Instagram, X, YouTube, TikTok, Discord and Reddit. About Elegoo Founded in 2015, Elegoo is a rapidly developing brand in the global smart manufacturing industry, specializing in R&D, manufacturing, and sales of consumer-grade 3D printers, laser engravers, STEM kits, and other smart technology products. Located in Shenzhen, the Silicon Valley of China, the company has sold millions of products across more than 90 countries and regions. In 2024, the company's total sales revenue surpassed 200 million USD, with more than 700 employees and nearly 30,000 square meters of office and manufacturing area. With a focus on programming and 3D printing technology, Elegoo provides unique and smart creation spaces for diverse consumers to enhance personalized experiences.
Artificial intelligence streamlines the optimisation of bioprinting parameters for oral soft tissue grafts, reducing time and resource demands while enabling efficient, personalised dental treatments SINGAPORE, April 4, 2025 /PRNewswire/ -- A team of researchers from the National University of Singapore (NUS) has developed a method to fabricate personalised gingival (gum) tissue grafts using an innovative combination of 3D bioprinting and artificial intelligence (AI). Led by Assistant Professor Gopu Sriram from NUS Faculty of Dentistry, the team's approach presents a more customisable and less invasive alternative to traditional grafting methods, which often involve harvesting tissue from the patient's mouth — a process that can be both uncomfortable and constrained by the availability of suitable tissue. The 3D bioprinting and AI-enabled technique has the potential to address key challenges in dental procedures more effectively, such as repairing gum defects caused by periodontal disease or complications from dental implants. For instance, by enabling the precise fabrication of tissue constructs tailored to individual patients, the method can significantly improve treatment outcomes, reduce patient discomfort, and minimise the risk of complications, such as infections, during recovery. The team's research was published in the journal Advanced Healthcare Materials on 17 December 2024, and was supported by grants from National Additive Manufacturing Innovation Cluster (NAMIC) and National University Health System (NUHS). Turbocharging the bioprinting process with AI Gum tissue grafts are essential in dental care, particularly for addressing mucogingival defects such as gum recession, and complications arising from periodontal disease or dental implants. Typically, these grafts are harvested from the patient's mouth. Though effective, these procedures come with significant drawbacks: patient discomfort, limited tissue availability, and a higher risk of postoperative complications. To overcome these challenges, the researchers turned to 3D bioprinting, a technique that fabricates custom-made tissue grafts tailored to the specific dimensions of each patient's defect. They developed a specialised bio-ink which supports the growth of healthy cells, while also ensuring the material can be printed accurately and holds its shape and structure. However, the viability of 3D bioprinting is only as good as the parameters applied during the process. Factors such as extrusion pressure, print speed, nozzle dimensions, bio-ink viscosity and printhead temperature all play a crucial role in determining the final properties and performance of the printed component. Tuning these parameters has traditionally been done through tedious, manual trial-and-error experiments that are extremely time- and resource-consuming. "To speed up the 3D bioprinting process, we integrated AI into our workflow to address this critical bottleneck," said Professor Dean Ho, Head of the Department of Biomedical Engineering in the College of Design and Engineering at NUS, and co-corresponding author of the research paper. "This approach greatly streamlines the process by reducing the number of experiments needed to optimise the bioprinting parameters — from potentially thousands to just 25 combinations," added Prof Ho, who is also Director of the Institute for Digital Medicine (WisDM) at NUS Yong Loo Lin School of Medicine, and N.1 Institute for Health (N.1) at NUS. This tremendous efficiency boost afforded by the team's AI-driven workflow saves time and resources while ensuring the creation of tissue constructs with precise dimensions and structural integrity. "Our study is among the first to specifically integrate 3D bioprinting and AI technologies for the biofabrication of customised oral soft tissue constructs," said Asst Prof Sriram, who is also the Thrust Co-Lead of Dental and Craniofacial 3DP Applications at NUS Centre for Additive Manufacturing (AM.NUS). "3D bioprinting is by far more challenging than conventional 3D printing because it involves living cells, which introduce a host of complexities to the printing process." The bioprinted gum tissue grafts exhibited strong biomimetic properties, maintaining over 90% cell viability immediately after printing and throughout an 18-day culture period. The grafts also retained their shape and structural integrity, while histological analyses confirmed the presence of key proteins and a multi-layered structure closely resembling natural gum tissue. The future of dental care In dentistry, the ability to produce personalised gum tissue grafts with improved efficiency, structural integrity, and biomimetic properties could address longstanding clinical challenges associated with periodontal diseases and dental implants. "This research demonstrates how AI and 3D bioprinting can converge to solve complex medical problems through precision medicine," added Asst Prof Sriram. "By optimising tissue grafts for individual patients, we can reduce the invasiveness of dental procedures while ensuring better healing and recovery." Excitingly, the potential implications of this research extend beyond dentistry. "3D bioprinting allows us to create tissue grafts that precisely match the dimensions of a patient's wounds, potentially reducing or eliminating the need to harvest tissue from the patient's body," said Asst Prof Sriram. "This level of customisation minimises graft distortion and tension during wound closure, reducing the risk of complications, surgery time and discomfort to the patients." said Dr Jacob Chew, a periodontist, co-investigator of the study, and Academic Fellow at NUS Faculty of Dentistry. Furthermore, the scarless healing characteristics of oral tissue provide a unique advantage, as insights from this study could inform the fabrication of similar grafts for other barrier tissues, such as skin, potentially aiding in the scarless healing of skin wounds. Future research will focus on translating these findings from bench to bedside. The team plans to conduct in vivo studies to assess the integration and stability of the grafts in oral environments. They also aim to explore the integration of blood vessels into the grafts through multi-material bioprinting to create more complex and functional constructs. With these developments, the researchers hope to advance the field of regenerative dentistry while paving the way for broader applications in tissue engineering. Read more at: https://news.nus.edu.sg/combining-3d-bioprinting-with-ai-to-personalise-oral-soft-tissue-grafts.
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