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由PR Newswire 美通社張貼的訊息, 共 47028 篇 ,以下為 7849 - 7872 篇 訂閱此列表,掌握最新動態
Landis+Gyr Awarded EcoVadis Platinum Medal for Outstanding Sustainability Performance

CHAM, Switzerland, Sept. 26, 2024 /PRNewswire/ -- Landis+Gyr AG (SIX: LAND), a global leader in energy management solutions, today announced it has received the prestigious Platinum medal from EcoVadis, the highest possible distinction awarded under this rating. EcoVadis Platinum Sustainability Rating Since its last assessment, Landis+Gyr improved its overall score from 72 to 80, placing it within the top1% of companies rated by EcoVadis in its peer group. This recognition underscores the company's strong commitment to sustainability and the successful integration of sustainable practices across its business operations. "Our improved EcoVadis rating is a testament to our ongoing efforts to lead the industry in sustainability," said Werner Lieberherr, CEO of Landis+Gyr. "It validates our commitment to incorporating sustainability into everything we do, from environmental stewardship to ethical practices and responsible procurement." The EcoVadis assessment evaluates 21 sustainability criteria across four core themes: 'Environment', 'Labor & Human Rights', 'Ethics' and 'Sustainable Procurement'. This year, Landis+Gyr received its highest score in the 'Environment' dimension (90 out of 100), followed by 'Labor & Human Rights' and 'Sustainable Procurement' (80 out of 100 each) and 'Ethics' (70 out of 100). The assessment helps the company measure performance, uncover risks and identify where and how it can improve its overall ESG impact going forward. About Landis+Gyr Landis+Gyr is a leading global provider of integrated energy management solutions. We measure and analyze energy utilization to generate empowering analytics for smart grid and infrastructure management, enabling utilities and consumers to reduce energy consumption. Our innovative and proven portfolio of software, services and intelligent sensor technology is a key driver to decarbonize the grid. Having avoided around 9 million tons of CO2 in FY 2023, Landis+Gyr manages energy better – since 1896. With sales of USD 2.0 billion in FY 2023, Landis+Gyr employs around 6,900 talented people across five continents. For more information, please visit our website www.landisgyr.com. About EcoVadis Since its founding in 2007, EcoVadis has grown into a globally trusted provider of business sustainability ratings with a network of more than 130,000 rated companies. EcoVadis' business sustainability ratings are based on international sustainability standards such as the Ten Principles of the UN Global Compact, the International Labour Organization (ILO) conventions, the Global Reporting Initiative (GRI) standards and the ISO 26000 standard. The ratings provide an evidenced-based analysis on performance and an actionable roadmap for continuous improvement. Learn more at www.ecovadis.com. Media Contact Eva BorowskiSVP Investor Relations & Corporate Communicationspr@landisgyr.com    

文章來源 : PR Newswire 美通社 發表時間 : 瀏覽次數 : 192 加入收藏 :
Hong Kong's Labour Department Certifies SU Group Under Good Employer Charter

HONG KONG, Sept. 26, 2024 /PRNewswire/ -- SU Group Holdings Limited (Nasdaq: SUGP) ("SU Group" or the "Company"), an integrated security-related engineering services company in Hong Kong, today announced Hong Kong's Labour Department certified its wholly owned unit, Shine Union Limited, under the Good Employer Charter 2024. The Good Employer Charter 2024 recognizes that human capital is one of the most important assets of an enterprise. As employees are attaching increasing importance to work-family balance, adopting good human resource management practices is essential to recruiting and retaining manpower in various trades and industries. The adoption of family-friendly employment practices helps relieve pressure on employees shouldering both work and family responsibilities.  It can also foster employees' sense of belonging to the company and enhance their efficiency which in turn will boost the competitiveness of the company, leading to a win-win situation for all. SU Group's Chairman and CEO, Dave Chan, commented, "We are honored to receive the Good Employer Charter 2024, which recognizes the high priority we place on family-friendly policies due to their compelling strategic, social and ethical reasons. These policies are win-win strategies as we are able to support employees in managing family responsibilities while benefiting the company through improved engagement, retention, and overall workplace culture. The bottom-line is, offering family-friendly benefits makes our company more attractive to job candidates, enhances our reputation as an employer of choice, and employees are more likely to stay with us for longer-term knowing we support their work-life balance needs." About SU Group Holdings Limited SU Group (Nasdaq: SUGP) is an integrated security-related services company that primarily provides security-related engineering services, security guarding and screening services, and related vocational training services in Hong Kong. Through its subsidiaries, SU Group has been providing turnkey services to the existing infrastructure or planned development of its customers through the design, supply, installation, and maintenance of security systems for over two decades. The security systems that SU Group provides services include threat detection systems, traffic and pedestrian control systems, and extra-low voltage systems in private and public sectors, including commercial properties, public facilities, and residential properties in Hong Kong. For more information visit www.sugroup.com.hk. Forward-Looking Statements Certain statements in this press release are forward-looking statements as defined by the Private Securities Litigation Reform Act of 1995. These forward-looking statements involve known and unknown risks and uncertainties and are based on the Company's current expectations and projections about future events that the Company believes may affect its financial condition, results of operations, business strategy and financial needs. Investors can identify these forward-looking statements by words or phrases such as "anticipate," "estimate," "plan," "project," "continuing," "ongoing," "expect," "we believe," "we intend," "may," "should," "will," "could" and similar expressions. These statements are subject to uncertainties and risks including, but not limited to, the following: the Company's ability to renew contracts with recurring customers; the Company's ability to secure new contracts; the Company's ability to accurately estimate risks and costs and perform contracts based on the Company's estimates; the Company's relationship with the Company's suppliers and ability to manage quality issues of the systems; the Company's ability to obtain or renew the Company's registrations, licenses, and certificates; the Company's ability to manage the Company's subcontractors; the labor costs and the general condition of the labor market; the Company's ability to effectively manage inventories; the Company's ability to compete effectively; the Company's dependence on a small number of suppliers for a substantial portion of the Company's supplies; the Company's ability to successfully manage the Company's capacity expansion and allocation in response to changing industry and market conditions; implementation of the Company's expansion plans and the Company's ability to obtain capital resources for planned growth; the Company's ability to acquire sufficient products and obtain equipment and services from the Company's suppliers in suitable quantity and quality; the Company's dependence on key personnel; the Company's ability to expand into new businesses, industries, or internationally and to undertake mergers, acquisitions, investments, or divestments; changes in technology and competing products; general economic and political conditions, including those related to the security-related engineering services industry; possible disruptions in commercial activities caused by events such as natural disasters, terrorist activities, political, economic, and social instability, and fluctuations in foreign currency exchange rates, and assumptions underlying or related to any of the foregoing and other risks contained in reports filed by the Company with the U.S. Securities and Exchange Commission (the "SEC"), including the Company's most recently filed Annual Report on Form 20-F and its subsequent filings. The Company undertakes no obligation to update or revise publicly any forward-looking statements to reflect subsequent occurring events or circumstances, or changes in its expectations, except as may be required by law. Although the Company believes that the expectations expressed in these forward-looking statements are reasonable, it cannot assure you that such expectations will turn out to be correct, and the Company cautions investors that actual results may differ materially from the anticipated results and encourages investors to review other factors that may affect its future results in the Company's registration statement and other filings with the SEC.

文章來源 : PR Newswire 美通社 發表時間 : 瀏覽次數 : 243 加入收藏 :
WIMI develops glasses product "WiMi HoloAR Lens" to enhance wearable user experience

BEIJING, Sept. 26, 2024 /PRNewswire/ -- WiMi Hologram Cloud Inc. (NASDAQ: WIMI) ("WiMi" or the "Company"), a leading global Hologram Augmented Reality ("AR") Technology provider, today announced the release of "WiMi HoloAR lens", an augmented reality (AR) headset for the consumer market, to further strengthen the hardware and software development of the underlying holographic technology and to expand the user experience of holographic AR technology in the wearable field. This AR product from WIMI, WiMi HoloAR Lens, is a split glasses compatible with dual cameras and 6dof (degrees of freedom) spatial localization solution features. It facilitates the full utilization of spatial interaction and is suitable for multiple scenarios such as spatial interaction and spatial localization. For the new applications, the holographic AR technology has been upgraded, which much benefits multi-application development and promotion of user experience of the Metaverse. Parameters of WiMi HoloAR Lens are better than products of same type, and the product is a more user-friendly and easy-to-wear AR display device on projection screen. It can be extended to connect to personal computers, drones, Android & IOS smartphones, appearing to be a portable and mobile smart display device in multiple scenarios. Compared with the viewing angle of 30-55 degree in the industry, this product has a wider vision of 63 degrees, greatly enhancing the product's visual immersion. And the product shows a 600-inch long giant screen display, 1920*1080p high-definition picture, a contrast ratio of 50000/1, and 80 million full colors. Combined with the high-brightness screen of 1800nit and the high refresh rate of 90Hz, the product allows users to obtain a clearer and more realistic display effect. The whole machine weighs only 78g, and the pressure on the user's face is very low, comfortable to wear, suitable for daily travel, high-speed trains, and airplanes, subway, outdoor virtual communication and video conference, besides home fitness, home education and many other scenes. The optical solution integrates refractive error adjustment ranging from 0 degree to 500 degree. Users can directly view the virtual image clearly without a myopia. The product has a strong advantage of expansion and upgrade, and if collocated with 6dof dual handles, the interactive scenes can be realized and create the entertainment application scenes of the product, even supporting full-stack for Steam games. It is expected to become the main entrance of holographic new AR technology of Metaverse in communication, social interaction and entertainment interaction. Shi Shuo, CEO of WiMi, said: "WiMi HoloAR Lens, accelerates the iteration in terms of image color management, dockable devices and wearing experience, and holographic AR technology implantation. We have laid a solid foundation in the expansion of the Metaverse scene. With the popularization of Metaverse and technological breakthroughs, people's demand for AR and VR products will continue to grow. WIMI's holographic XR(AR/VR/MR) head-mounted display product, like WiMi Hologram SoftLight, has been licensed and approved by the Federal Communications Administration (FCC) to enter the US market. The new WiMi HoloAR Lens will also be widely used in fields of virtual social networking, virtual entertainment, virtual education, virtual communications, etc. " About WIMI Hologram Cloud WIMI Hologram Cloud, Inc. (NASDAQ:WIMI) is a holographic cloud comprehensive technical solution provider that focuses on professional areas including holographic AR automotive HUD software, 3D holographic pulse LiDAR, head-mounted light field holographic equipment, holographic semiconductor, holographic cloud software, holographic car navigation and others. Its services and holographic AR technologies include holographic AR automotive application, 3D holographic pulse LiDAR technology, holographic vision semiconductor technology, holographic software development, holographic AR advertising technology, holographic AR entertainment technology, holographic ARSDK payment, interactive holographic communication and other holographic AR technologies. Safe Harbor Statements This press release contains "forward-looking statements" within the Private Securities Litigation Reform Act of 1995. These forward-looking statements can be identified by terminology such as "will," "expects," "anticipates," "future," "intends," "plans," "believes," "estimates," and similar statements. Statements that are not historical facts, including statements about the Company's beliefs and expectations, are forward-looking statements. Among other things, the business outlook and quotations from management in this press release and the Company's strategic and operational plans contain forward−looking statements. The Company may also make written or oral forward−looking statements in its periodic reports to the US Securities and Exchange Commission ("SEC") on Forms 20−F and 6−K, in its annual report to shareholders, in press releases, and other written materials, and in oral statements made by its officers, directors or employees to third parties. Forward-looking statements involve inherent risks and uncertainties. Several factors could cause actual results to differ materially from those contained in any forward−looking statement, including but not limited to the following: the Company's goals and strategies; the Company's future business development, financial condition, and results of operations; the expected growth of the AR holographic industry; and the Company's expectations regarding demand for and market acceptance of its products and services. Further information regarding these and other risks is included in the Company's annual report on Form 20-F and the current report on Form 6-K and other documents filed with the SEC. All information provided in this press release is as of the date of this press release. The Company does not undertake any obligation to update any forward-looking statement except as required under applicable laws.

文章來源 : PR Newswire 美通社 發表時間 : 瀏覽次數 : 233 加入收藏 :
香港數碼娛樂協會 於「2024東京電玩展」設「香港館」

第四屆「香港遊戲優化和推廣計劃」精選本地遊戲初創企業展示香港在遊戲創意與新技術 香港2024年9月26日 /美通社/ -- 由香港數碼娛樂協會主辦、文創產業發展處為主要贊助機構的「香港遊戲優化和推廣計劃」(優化和推廣計劃),於2024東京電玩展 (9月26日至29日) 再度設立香港館,為第四屆優化和推廣計劃入選的12間香港初創遊戲公司提供展示平台,向全球同業及遊戲愛好者展示香港的多元化原創遊戲作品及創新技術。參展的香港公司將帶同他們全新並獲優化和推廣計劃支援的原創遊戲,爭取與國際業界持份者交流合作,開拓更廣闊的市場。 一年一度的東京電玩展於今天開始一連四日在日本千葉幕張展覽館舉行。作為亞洲最大規模的遊戲盛事之一,東京電玩展匯聚了全球頂尖遊戲開發商、業界人士及遊戲愛好者,共同探索最新、最精彩的遊戲作品和創新技術。為隆重其事,大會邀請了文創產業助理專員曹黎淑霞女士、香港駐東京經濟貿易辦事處歐慧心女士, JP、香港貿易發展局日本首席代表游紹斌先生,及香港遊戲開發聯盟主席劉嘉承先生,連同香港數碼娛樂協會主席彭子傑先生,於東京主持「香港館」的剪綵儀式。 2024年東京電玩展的香港館佔地約100平方米,展出12款最新的香港原創遊戲。遊戲類型包括角色扮演、2D動作、旋轉控制手機節奏遊戲、休閒遊戲、解謎冒險、射擊遊戲等。 第四屆「香港遊戲優化和推廣計劃」入選公司名單 (排名按公司英文名順序排列) 公司名稱 指定遊戲名稱 遊戲類別 Daytech HK Limited 9貓特攻隊 射擊遊戲  感受遊戲有限公司 生嚿叉燒好過生你 冒險電腦遊戲 Finifugu Games Limited Animal Express 輕鬆模擬遊戲 紛意思遊戲有限公司 連擊萌獸 益智遊戲 Gianthouse Limited Soul Magic Web3角色扮演遊戲 LEAP STUDIO LIMITED 墨境 Roguelite 動作遊戲 ML INTERACTIVE LIMITED Winning Derby 勝利の少女: 御駖少女培育模擬遊戲 培育模擬遊戲 Realm of Alters Limited 第九機關 角色扮演遊戲 動境天地有限公司 次元競技場 沉浸式多人MR 互動遊戲 随意萌工作室有限公司 公主戰士模擬器 Roblox 模拟器 華城投資有限公司 美女特工 角色扮演遊戲 Xanadoo Limited Matr1x Fire 射擊遊戲 免責聲明:香港特別行政區政府僅為本項目提供資助,除此之外並無參與項目。在本刊物/活動內(或由項目小組成員)表達的任何意見、研究成果、結論或建議,均不代表香港特別行政區政府、文化體育及旅遊局、文創產業發展處、「創意智優計劃」秘書處或「創意智優計劃」審核委員會的觀點。

文章來源 : PR Newswire 美通社 發表時間 : 瀏覽次數 : 386 加入收藏 :
「秋季家居博覽2024」正式開幕

新增樂齡展區 「大家居」概念成新趨勢 香港2024年9月26日 /美通社/ -- 由展覽集團舉辦、今年最後一個一站式家居博覽「秋季家居博覽2024」(「博覽」) 今日起至9月29日(四至日)一連四日假 香港會議展覽中心展覽廳5BCDE舉行,承接六月份「香港家居博覽」的熱潮,今次博覽場地增加兩個展覽廳,設置七大展區涵蓋傢俱、室內設計、建材、環保產品、智慧家居等多個領域,合共超過550個展位,為全港市民提供了一站式的家居裝修和產品選擇平台。博覽今年更特別增設「樂齡展區」,以滿足長者對家居產品和服務的需求,提供更好的生活品質。入場人士更有機會參與簽賬大抽獎及每日現場「家居智慧王」有獎問答遊戲,贏取東京、首爾及台北雙人來回機票、大型家庭電器、家居禮品以及超市禮券等總值近20萬元豐富禮品。 秋季家居博覽2024開幕儀式邀請香港特別行政區政府商務及經濟發展局副局長陳百里、香港特別行政區立法會建築、測量、都市規劃及園境界功能組別議員謝偉銓、香港工業總會第31分組(設計)主席張益麟、香港工業專業評審局主席梁勵、香港傢俬裝飾廠商總會主席鄺錦明、香港工業總會第10分組:香港家具協會副主席呂紹雄、Mastercard香港及澳門資深副總裁(業務拓展)李浩強、利嘉閣地產市場推廣、傳訊及研究部高級聯席董事關碧紅、香港長者產業聯會副會長鍾明志、展覽集團主席王學譜及總經理朱雪玲一同主禮。 展覽集團主席王學譜表示:「隨著美國開始減息,香港也跟隨減息,這對供樓人士來說是一個積極的信號,樓宇交投氣氛改善,對家居消費市場必然有正面刺激及影響。秋季家居博覽2024是今年最後一個一站式家居博覽,因應香港市場需要,我們特別加開兩個展館,展位數量超過550個,更特別增設的『樂齡展區』以滿足長者對家居產品和服務的需求,未來,我們將積極推動『大家居』概念,並將個性化訂制、樂齡傢俱、綠色環保產品及智能家居作為行業發展的新方向,以實現家居行業的可持續發展。」 「秋季家居博覽2024」針對香港中高端消費、新居入伙、家居裝修市場設置七大展區,入伙、裝修人仕可藉此一次性搜羅城中最新傢俬 / 戶外傢俬、室內設計 / 裝修工程、建材 / 建築物料、環保 / 綠化產品、床褥 / 梳化、浴室 / 寢室 / 廚房 設備、智能家居 / 家電產品、家品藝術擺設、長者家居設備及設計師新產品的產品及服務資訊。多間室內設計、裝修公司和各類型家居服務展商參展,根據消費者的個人喜好,訂制一流的家居設計、家品擺設和裝修建材。同時,樂齡展區將展示,從智慧居家安老、自立支援、遠程復康訓練、健康篩查及監測等範疇,支援長者生活,為香港市民創造出一個既舒適又具有個性的居住環境。 博覽設有大型電器Outlet東林商貿有限公司 (展位編號:5E-N61) 提供電器開倉大優惠,包括電視機、多功能陶瓷電子燉煲、微波爐及風扇等每日限量優惠產品低至一折起。博覽期間設有免費專業講座諮詢,邀請了各行各業的專家,分享家居玄學、家居收納、翻新或新居入伙小貼士等主題,包括玄學顧問司徒法正師傅大談【2025年12生肖大旺福氣風水擺設】、香港專業整理收納協會副會長Jeffery Yip分享【巧用現有資源:打造無壓力家居的整理法】、全職收納師More Than Tidy Up 創辦人Kaye Li分享【家居收納用品挑選攻略:從挑選到應用】。 現場亦設有《Mastercard®卡簽賬刮刮卡大抽獎》凡顧客憑單一發票以Mastercard卡於展覽會場內指定攤位簽賬消費每$500,均可獲一次「刮刮卡大抽獎」機會,$1000為兩次抽獎機會,如此類推,每張發票最多可獲10次抽獎機會,有機會贏取東京、首爾及台北雙人來回機票、雪櫃、電視及超市現金劵等總值近20萬元獎品,即刮即知抽獎結果。入場人士更有機會參與每日現場「家居智慧王」 (展位編號:5B-A22, 5E-S11) 有獎問答遊戲,於指定時間在有獎遊戲區參與當節遊戲並於限時內回答問題,贏取超過200份豐富禮品。 秋季家居博覽2024 日期 2024年9月26日至29日 (星期四至日) 時間 9月26至28日 (星期四至六):上午11時至晚上8時 9月29日 (星期日):上午11時至晚上7時 地點 灣仔博覽道1號香港會議展覽中心展覽廳5BCDE(會展站B3或灣仔站A5出入口) 網址 https://www.exhibitiongroup.com.hk/exhibitions/inhomeaut2024    秋季家居博覽2024今日正式開幕。(前排左起)展覽集團總經理朱雪玲、利嘉閣地產市場推廣、傳訊及研究部高級聯席董事關碧紅、香港工業總會第10分組:香港家具協會副主席呂紹雄、香港工業專業評審局主席梁勵、香港特別行政區立法會建築、測量、都市規劃及園境界功能組別議員謝偉銓、香港特別行政區政府商務及經濟發展局副局長陳百里、展覽集團主席王學譜、香港工業總會第31分組(設計)主席張益麟、香港傢俬裝飾廠商總會主席鄺錦明、Mastercard香港及澳門資深副總裁(業務拓展)李浩強、香港長者產業聯會副會長鍾明志。 關於展覽集團 展覽集團有限公司為香港知名的展覽公司之一。團隊核心成員組成自2003年,集合一群富有新思維、經驗豐富及專業的展覽人才,是一家領先的活動管理公司,專門策劃和營運世界級的公眾展覽、會議和商貿展覽,主題涵蓋多個不同的行業。憑藉多年的行業經驗,致力發展展覽及市場推廣業務,在展覽業內享負盛名。 本公司創辦多個不同主題類型的展覽及市場推廣項目,不但得到眾多商界及參展商支持,更有效地吸引大量公眾人士參與,每項活動均好評如潮、參展商在產品推廣及銷售兩方面均取得雙贏成果。著名展覽包括香港寵物節、香港家居博覽、優質寵物用品展、香港貓迷博覽會、香港旅遊博覽會、課外活動節、香港戶外用品及運動博覽等等,本公司於近年榮獲得多個獎項,當中包括「Outstanding Award for Pandemic Resilience」、「ESG Commendation Awards」、「創新博覽策劃」等業務發展成果得到各界認同。 傳媒垂詢,請聯絡: Market Hubs Holdings Limited Lierence Li 李鑒泉 Ginger Kiang +852 3998-4900 +852 3998-4900 lierence@markethubsgroup.com ginger@markethubsgroup.com  Debbie So +852 3998-4900 debbie@markethubsgroup.com  

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愛科百發宣布抗呼吸道合胞病毒(RSV)新藥齊瑞索韋治療嬰幼兒患者3期臨床研究結果發表於《新英格蘭醫學雜志》

上海2024年9月26日 /美通社/ -- 北京時間2024年9月27日,愛科百發宣布齊瑞索韋治療嬰幼兒呼吸道合胞病毒(RSV)感染患者的3期臨床研究結果全文發表於《新英格蘭醫學雜志》(The New England Journal of Medicine, NEJM)。這是《新英格蘭醫學雜志》發表的首個中國自主研發的兒童創新藥臨床研究,也是全球首個治療RSV病毒感染靶向藥的3期臨床試驗結果。此次發表由首都醫科大學附屬北京兒童醫院趙順英教授為文章第一作者,首都醫科大學附屬北京兒童醫院倪鑫教授,四川大學華西醫學院附屬第二醫院劉瀚旻教授和愛科百發鄔征博士為共同通訊作者。為此,《新英格蘭醫學雜志》專門發表Edward Walsh教授的社論文章「逐步邁向治療RSV感染的有效抗病毒藥物」,高度評價齊瑞索韋治療嬰幼兒RSV感染的3期臨床研究「結果令人鼓舞」。 RSV是嬰幼兒呼吸道感染住院的首要檢出病原。尤其在冬春季流行季節,RSV感染可導致嬰幼兒發生毛細支氣管炎、肺炎等嚴重呼吸系統疾病,造成高昂的醫療花費,對於早產及患先天性疾病的嬰幼兒甚至可能危及生命,愈後嬰幼兒病人再發喘息,哮喘等呼吸道疾病較健康兒童顯著增加。目前全球范圍內尚無治療RSV感染的特效藥物獲批上市。這項研究積極結果的公布,標志著中國科學家在RSV感染領域取得了「從無到有」的突破性創新成果,走在全球抗RSV新藥研發的前列。這項研究是由首都醫科大學附屬北京兒童醫院倪鑫/趙順英教授團隊牽頭開展,全國30家兒童醫院或綜合醫院兒科參與的臨床3期研究。研究結果顯示齊瑞索韋安全有效,能夠顯著降低RSV感染嬰幼兒的病毒載量,改善臨床症狀。 這項全國多中心、隨機、雙盲、安慰劑對照的3期臨床試驗共納入了311名1~24月齡因RSV感染住院的嬰幼兒患者,以2:1的比例隨機分配到齊瑞索韋治療組和安慰劑對照組,開展為期5天的治療。主要評估指標是治療48小時後,毛細支氣管炎臨床評分較基線的變化。關鍵次要終點是治療96小時後RSV病毒載量較基線的改變。 研究結果: 療效顯著:與安慰劑相比,齊瑞索韋治療組在第一次給藥48小時後的毛細支氣管炎臨床評分平均降低3.4分,而安慰劑組降低2.7分,兩者差異達到0.8分,具有統計學意義(P=0.002)。 病毒載量顯著降低:齊瑞索韋治療組在第一次給藥96小時後的RSV病毒載量較基線平均下降2.5 log10 copies/mL,安慰劑組則下降1.9 log10 copies/mL,差異為0.6 log10 copies/mL,即多降77%(P=0.006)。 安全性良好:齊瑞索韋治療組的藥物相關不良事件發生率為16%,安慰劑組為13%,未發現嚴重的藥物相關不良事件。 研究結果表明,齊瑞索韋作為一款新型口服抗病毒藥物,在治療RSV感染的嬰幼兒中顯示出了積極的臨床效果。藥效主要表現在能夠顯著降低毛細支氣管炎的各項臨床評分,並且降低病毒載量。此外,該藥物的安全性得到了驗證,藥物相關的不良事件發生率與安慰劑組相比沒有顯著差異。 首都醫科大學附屬北京兒童醫院院長倪鑫教授表示:「RSV感染一直是兒科醫療領域的一項嚴峻挑戰,這種病毒不僅對兒童的健康構成威脅,也給醫療系統帶來了沉重的負擔。長久以來,我們一直在尋找一種安全有效的治療手段。今天,我們團隊在這一領域取得了重大進展。我們感謝新英格蘭醫學雜志對這項臨床研究的認可和鼓勵。這是全球首個在RSV感染住院嬰幼兒中開展並取得積極結果的口服靶向抗病毒藥物的3期臨床試驗。我相信,這項研究成果將為全球數百萬受RSV病毒影響的家庭帶來福音,也期待齊瑞索韋早日獲批上市應用於臨床,使中國和全球的RSV兒童患者可以健康成長。」 愛科百發CEO鄔征博士表示:「齊瑞索韋的3期臨床研究結果令人鼓舞,研究證實了齊瑞索韋是一種安全有效的RSV抗病毒治療藥物。作為研究的申辦方,我們深深地感謝所有積極參與這項研究的患者和家長,研究者專家團隊,及各方合作伙伴。我們會繼續努力,與兒童呼吸界專家合作,在國家藥品監督管理局的指導下,推動該藥物的進一步研發和臨床應用。我們將努力不懈繼續致力於兒童創新藥的研發,為兒童患者創造一個更加健康幸福的未來。」 關於齊瑞索韋 齊瑞索韋是一款全新的靶向RSV融合蛋白小分子抑制劑,它通過與病毒的F蛋白結合從而阻止病毒侵入人體細胞。它也可以阻斷病毒通過細胞與細胞間的融合,即形成「合胞體」,一種RSV感染細胞的特征,從而實現抗病毒效果。 齊瑞索韋是全球首個成功完成3期臨床試驗並獲得積極結果的靶向RSV的特效抗病毒藥物,也是首個在中國發明和開發,並拓展到全球的兒童創新藥。同時,齊瑞索韋是首個獲國家藥品監督管理局(NMPA)「突破性治療品種」認定的非腫瘤創新藥。 關於愛科百發 愛科百發是一家創新生物醫藥公司,專注於兒童和呼吸疾病領域未被滿足的重大臨床需求。自2014年成立以來,公司在具有全新作用機制的創新藥物研發領域擁有多項核心技術和全球專利,通過自主研發和外部引進相結合的研發模式,開發出高度差異化的豐富產品管線。核心產品齊瑞索韋 (愛司韋™) 是全球范圍內首款完成3期臨床試驗並取得積極結果的靶向RSV特效抗病毒藥物,也是首個納入國家突破性治療品種的非腫瘤新藥。另一個接近商業化的產品是已獲得FDA批准的兒童多動症新藥AK0901(愛智達™),愛科百發擁有其在大中華區的開發和營銷權。公司還擁有多個具有同類最佳或同類首創潛力的新藥正處於臨床試驗開發階段。 愛科百發與羅氏/基因泰克等跨國藥企、美國學術機構Scripps研究所、中國科學院微生物研究所、國內外生物技術公司,及CRO建立了戰略合作關系。  公司詳情,請訪問網站:www.arkbiosciences.com  投資者垂詢:IR@arkbiosciences.com

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