本網站使用瀏覽器紀錄 (Cookies) 來提供您最好的使用體驗，我們使用的 Cookie 也包括了第三方 Cookie。相關資訊請訪問我們的隱私權與 Cookie 政策。如果您選擇繼續瀏覽或關閉這個提示，便表示您已接受我們的網站使用條款。 關閉
HEZE, China, Aug. 7, 2024 /PRNewswire/ -- Since the beginning of this year, the State Grid Chengwu County Power Supply Company has diligently studied and implemented the legal governance concepts. The company has actively engaged in the initiative to deepen and enhance the reform of state-owned enterprises, establishing a comprehensive and efficient "big compliance" management system to provide robust legal support for stable operations. In advancing the reform of state-owned enterprises, the company has firmly embraced the integration of business operations with legal principles. It has developed a compliance management organizational structure centered around establishing a strong legal team, strictly implementing procedures, constructing a full-cycle compliance control mechanism, and forming a stringent supervision system. Responsibilities and collaborative duties for compliance management have been clearly defined for the responsible departments and the leading compliance departments. The company actively identifies legal and regulatory issues, rigorously enforces accountability, and has constructed a "three-line defense" pattern for compliance management. Additionally, focusing on the principles of "respecting, learning, adhering to, and applying the law," the company has enhanced compliance training. It brings legal education, compliance training, and legal advocacy directly to all levels of staff, implementing initiatives like integrating compliance into party branches and having secretaries discuss compliance to foster a culture of proactive compliance. Through methods like team "lecture halls" and business training, the company regularly conducts case discussions, compliance reviews, and case analyses. It carries out extensive dissemination of policies and procedures, using examinations to promote learning and enhance the conscientious implementation of systems by all employees. Furthermore, the company has established a "big supervision" system, where departments such as legal compliance, internal control, risk control, and inspections work in coordinated synergy. It strengthens integrated operations before, during, and after events, routinely conducts risk and hidden danger inspections and management, and pushes for proactive problem-solving. The company ensures timely correction of issues, preemptive problem-solving, and comprehensive risk notifications, supervision, and rectification implementation, thereby enhancing the risk and compliance awareness among all employees. Looking ahead, the company plans to establish and enforce an accountability system that is seamlessly integrated with performance evaluations, staff incentives, and penalties. It aims to excel in the "latter half" of compliance management, using cases to drive governance and governance to enhance efficiency, thereby advancing the construction of a law-based corporate entity.
Polyfunctionality correlates with a patient's remission lasting over 18 months with the CAR T cell therapy IRVINE, Calif., Aug. 7, 2024 /PRNewswire/ -- PeproMene Bio, Inc., a clinical-stage biotech company developing novel therapies for cancers and immune disorders, today announced that City of Hope-developed BAFF-R CAR T, known as PMB-CT01, demonstrated better polyfunctionality than CD19 CAR T cells, which are used in current Food and Drug Administration-approved CAR T cell therapies, according to a correlative study published in Blood Advances. Researchers used a single-cell platform, which found that PMB-CT01 CAR T cells, had more polyfunctionality, which is T cells' ability to perform several functions at the same time, than CD 19 CAR T cells. PMB-CT01 cells also produced more stimulatory cytokines, which can spur the immune system, and effector cytokines, which can directly kill cancer cells. Using the City of Hope-developed assay, researchers tested a BAFF-R CAR T cell product from a 57-year-old man with relapsed mantle cell lymphoma. The patient had not achieved remission with prior CD19 CAR T cell therapies. After receiving one infusion in City of Hope's Phase 1 trial using PMB-CT01 and experiencing minimal side effects, the man has been in complete remission over 18 months and continues to have undetectable cancer by sensitive molecular tests for minimal residual disease. The study reported robust indicators of polyfunctionality, which correlated with successful CAR T cell expansion post-infusion and the patient's ongoing remission. Researchers plan to use the assay to test CAR T cell products from five other patients in the trial, all of whom have experienced similar remissions to PMB-CT01. "We developed BAFFR-CAR T therapy as another treatment option for a significant number of patients with lymphomas and leukemias who relapse after receiving commercial CD19 CAR T cell therapy, and our results so far represent the ideal maximal efficacy with minimal toxicity," said Larry W. Kwak, M.D., Ph.D., vice president and deputy director of City of Hope's Comprehensive Cancer Center and PeproMene's scientific founder and compensated chair of its Scientific Advisory Board. Kwak has an equity interest in PeproMene. "We have developed a robust and reliable polyfunctional assay for CAR T cell products, with the potential to predict patient outcomes and accelerate the development of effective CAR T cell therapies." Elizabeth Budde, M.D., Ph.D., the trial's principal investigator, an associate professor of hematology and hematopoietic cell transplantation and the executive medical director for the Immune Effector Cell Therapy Program at City of Hope, presented initial trial results at the American Society of Hematology's conference in December 2023. "It's exciting to say that five patients with non-Hodgkin lymphoma and one with B-cell acute lymphoblastic leukemia have been treated with PMB-CT01 and 100% have demonstrated durable responses," Dr. Budde said. "Many of the trial patients relapsed had after CD19 CAR T therapy and/or were CD19 negative. PMB-CT01 could present a viable option for other patients who also face this dilemma." "This assay can be applied to current and future clinical trials to guide the development of PMB-CT01. PeproMene remains committed to the ongoing scientific and clinical development of this potentially promising new cell therapy" said Hazel Cheng Ph.D., COO of PeproMene Bio. About PMB-CT01 PMB-CT01 is a first-in-class, BAFF-R-targeted, autologous CAR T cell therapy. BAFF-R (B- Cell Activating Factor Receptor), a member of the tumor necrosis factor (TNF) receptor superfamily, is the main receptor for BAFF and is expressed almost exclusively on B cells. Since BAFF-R signaling promotes normal B-cell proliferation and appears to be required for B-cell survival, tumor cells are unlikely to escape therapy via loss of the BAFF-R antigen. This unique characteristic makes BAFFR CAR T therapy a highly promising option for treating B-cell malignancies. The BAFFR CAR was constructed using anti-BAFF-R single-chain fragment variable (scFv) antibodies and second-generation signaling domains CD3ζ and 4-1BB. Our research has demonstrated that BAFFR-CAR T cells effectively kill human lymphomas and leukemias both in vitro and in animal models. PeproMene Bio has licensed the intellectual property of PMB-CT01 from City of Hope. About PeproMene Bio PeproMene Bio, Inc. is a clinical-stage biotech company in Irvine, California developing novel therapies to treat cancers and immune disorders. PeproMene's lead candidate, PMB-CT01 (BAFFR-CAR T cells) is currently being investigated to treat relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL; NCT04690595) and B-cell non-Hodgkin lymphoma (B-NHL; NCT05370430) in phase 1 clinical trials. PeproMene Bio is also developing BAFFR Bispecific T Cell Engager and BAFFR-CAR NK cells. Contact: John Fry, john.fry@pepromenebio.com
SINGAPORE, Aug. 7, 2024 /PRNewswire/ -- Foreword The first half of 2024 has marked a period of significant growth and innovation in the cryptocurrency market. This report outlines HTX Ventures' key investment directions and maps out the investment outlook for the latter half of 2024. "HTX Ventures had a great first-half of 2024, following our objective of advancing blockchain technology and Web3 ecosystems, it was through active searching and curation that we found potential opportunities to invest in. These projects have been shortlisted as we believe that they offer innovations and infrastructure that will be essential to the development of Web3. "Edward, the Managing Partner at HTX Ventures said. "For the rest of 2024, we remain optimistic despite the market slowdown, and will continue our lookout for more great projects to invest in by staying committed to the long-term game and supporting front-end development. We have observed a positive innovation flywheel. Triggered by one successful business model and ecosystem, it will inspire many entrepreneurs and lead to long-term innovations within the ecosystem." Market Context Macro Market The cryptocurrency market has experienced significant growth during the first half of 2024. The approval of Bitcoin ETFs has opened the door to traditional finance for cryptocurrencies, injecting substantial liquidity and stabilizing Bitcoin prices between $60,000 and $70,000 from an average of $40,000. Additionally, the approval of ETH ETFs by the U.S. Securities and Exchange Commission has ushered cryptocurrencies into the ETF era, greatly lowering the investment threshold, though it may also bring more regulation and artificial volatility. As a major class of risky assets, cryptocurrency ETF price fluctuations will have a stronger positive correlation with other financial markets (such as stocks and bonds). It could cause crypto to be more easily manipulated by Wall Street. The Federal Reserve's interest rate policies also have a significant impact on the cryptocurrency market. The Federal Reserve's interest rates directly affect the liquidity of the U.S. dollar and related pegged currencies, which in turn directly influence the volatility of Bitcoin and other major cryptocurrencies. Comment on the August 5th Global Market Selloff Triggered by Japan's interest rate hike, poor U.S. corporate earnings, and unfavorable U.S. unemployment data, the market experienced excessive pessimism and a global selloff (exiting risk assets and moving into safe-haven assets) on August 5th. However, the U.S. economy has not actually entered a recession. More economic data, such as July and August's CPI and PCE data, ISM manufacturing and non-manufacturing indexes, and PMI data, is needed to clarify the economic situation. Currently, the market's rate cut expectation is overly optimistic, with the market pricing in a total rate cut of about 100 basis points before the end of the year. The Federal Reserve needs more evidence to make a drastic monetary policy decision. Additionally, market uncertainty has increased due to the U.S. election. Based on the above assessments, we believe that at least until September, crypto investors should not be overly pessimistic and blindly cut positions, nor should they chase highs. It is a good time to tap into cheap but high-quality business models. Position sizes should be moderate, leverage should be avoided, and investors should continuously update their understanding as new economic data is released to gain greater certainty. Project Building On the business side, the Ethereum Dencun upgrade in early 2024 enhanced the ETH ecosystem, improved Layer 2 usability and competitiveness, and opened up new opportunities for project chains. EigenLayer's innovative business model has introduced new use cases and revenue streams for secured network coins like Ethereum, prompting exploration of new applications for Bitcoin. The combination of AI Agents with blockchain is also bringing transparency and automatic execution for service requesters, providing a glimpse into the future of AI integration. HTX Ventures' Investment Focus in First Half of 2024: During this market cycle, HTX Ventures has been actively identifying and supporting innovative technologies and new business models. Committed to advancing blockchain technology, HTX Ventures offers comprehensive support to projects that expand the scope of Web3. In the first half of 2024, HTX Ventures made 23 strategic investments across a wide range of areas, including infrastructure, DeFi, the Bitcoin ecosystem, AI, DePIN, SocialFi, and more, with a strong focus on foundational infrastructure and base layer models. Impressed by the increasing talent in the Web3 builder community, particularly as experienced Web3 developers collaborate with Web2 professionals to address real user needs, HTX Ventures is excited to partner with passionate teams to build a more user-friendly Web3 ecosystem. There are six main tracks that we look into and believe will continue to be rewarding and flourishing during the latter half of 2024. These include BTCFi, Multichain Future Infrastructure, and User Experience Enhancement, Application Infrastructure Projects, New SocialFi and Community Applications, and DePIN. Read the full report here: https://htxventures.medium.com/htx-ventures-releases-2024-half-year-investment-report-highlighting-six-key-investment-directions-aa2e77b0a034 About HTX Ventures HTX Ventures, the global investment division of HTX, integrates investment, incubation, and research to identify the best and brightest teams worldwide. With more than decade-long history as an industry pioneer, HTX Ventures excels at identifying cutting-edge technologies and emerging business models within the sector. To foster growth within the blockchain ecosystem, we provide comprehensive support to projects, including financing, resources, and strategic advice. HTX Ventures currently backs over 300 projects spanning multiple blockchain sectors, with select high-quality initiatives already trading on the HTX exchange. Furthermore, as one of the most active FOF (Fund of Funds) funds, HTX Ventures invests in 30 top global funds and collaborates with leading blockchain funds such as Polychain, Dragonfly, Bankless, Gitcoin, Figment, Nomad, Animoca, and Hack VC to jointly build a blockchain ecosystem. Feel free to contact us for investment and collaboration at VC@htx-inc.com Company Website https://www.htx.com/ventures
VILNIUS, Lithuania, Aug. 7, 2024 /PRNewswire/ -- BingX, a global leading cryptocurrency exchange, proudly announces the launch of the Global Broker Program 3.0, featuring upgraded rewards and extensive exposure resources. This initiative aims to foster strong partnerships with broker platforms worldwide and incentivize their participation with attractive benefits. BingX Launches Global Broker Program 3.0 with Enhanced Rewards and Visibility Vivien Lin, Chief Product Officer of BingX, shared her thoughts on the launch of the Global Broker Program 3.0, explaining its potential to strengthen partnerships and drive innovation in the cryptocurrency trading space. "This upgraded program underscores our commitment to fostering a collaborative ecosystem and providing unparalleled support and rewards to our broker partners. The enhanced incentives and exposure resources will significantly benefit brokers, encouraging more to join and thrive on the BingX platform," Lin stated, looking forward to welcoming new partners and witnessing the positive impact of these advancements. The BingX Global Broker Program 3.0 introduces significant upgrades, with brokers now eligible to receive rewards up to 20,000 USDT. The program offers a comprehensive reward structure designed to encourage broker participation and active trading on BingX. Brokers can also earn additional rewards based on the transaction fees generated within the first few weeks of trading. The program also includes an attractive referral scheme. Brokers who successfully refer another broker to the program will receive a referral bonus package set to 2,000 USDT. This package includes 500 USDT in cash rewards, 500 USDT in trial funds, and 1,000 USDT in bonus funds, making it highly beneficial for brokers to bring their peers into the BingX ecosystem. BingX's previous broker programs have garnered substantial interest and established successful partnerships with other trading platforms. Utilizing this launch, BingX aims to expand its network of broker partners and build mutually beneficial relationships. The exchange invites brokers worldwide to join the new program and take advantage of enhanced rewards and exposure opportunities. About BingX Founded in 2018, BingX is a leading crypto exchange, serving over 10 million users worldwide. BingX offers diversified products and services, including spot, derivatives, copy trading, and asset management – all designed for the evolving needs of users, from beginners to professionals. BingX is committed to providing a trustworthy platform that empowers users with innovative tools and features to elevate their trading proficiency. In 2024, BingX proudly became the official crypto exchange partner of Chelsea Football Club, marking an exciting debut in the world of sports. For more information please visit: https://bingx.com/
BEIJING, Aug. 7, 2024 /PRNewswire/ -- In March 2019, Chinese President Xi Jinping received the original French version of An Introduction to The Analects of Confucius, published in 1688, from his French counterpart Emmanuel Macron, as a national gift. This precious gift is currently housed in China's National Library.  There is a prospect greater than the sea, and that is the sky; there is a prospect greater than the sky, and that is the human soul In May 2024, on the 60th anniversary of China-France diplomatic relations, Xi gifted Macron several Chinese translations of French novels. Bearing the fragrance of Eastern ink, these literary works returned to their place of origin. From six decades of friendship to a two-way journey of intellectual and cultural exchange, China and France have crafted a remarkable tale of civilizational dialogue. "There is a prospect greater than the sea, and that is the sky; there is a prospect greater than the sky, and that is the human soul." This is a quote by French writer Victor Hugo. On March 27, 2014, Xi quoted this in his speech at the UNESCO headquarters in Paris, in which he presented China's outlook on the term "civilization" to the world for the first time. He emphasized that, as we engage with different civilizations, we now need a mindset that is broader than the sky, one that transcends boundaries. We need to encourage different civilizations to respect one another and live together in harmony, while promoting exchange and mutual learning as bridges of friendship among peoples. Exchange and mutual learning are two strong forces driving human society as well as world peace. Since the 18th National Congress of the Communist Party of China in 2012, Xi has actively advocated for and promoted the exchange and mutual learning among different civilizations. He has proposed the concept of building a community with a shared future for humanity, as well as the Global Civilizations Initiative, contributing Chinese knowhow and advancing human civilization. China upholds the principle of promoting exchange through culture and fostering understanding through exchange. This demonstrates its respect and appreciation for other civilizations. Together with all parties, China seeks to create a tapestry of mutual learning and understanding among diverse civilizations. The world is currently undergoing great changes unseen in a century. Addressing common challenges and moving toward a better future together require not only the power of economy and technology, but also the combined strength of all the world's civilizations. As the futures of all countries are closely connected, we need a mindset that is broader than the sky, one that transcends boundaries. Inclusiveness, coexistence, exchange and mutual learning among different civilizations have an irreplaceable role in advancing humanity's modernization process and nurturing the colorful garden of world civilizations. Comments to zhangshsh@cicgamericas.com TikTokhttps://www.tiktok.com/@cachinachic/video/7386487829758528799?is_from_webapp=1&sender_device=pc&web_id=7227134149436605995 Xhttps://x.com/BeijingReview/status/1807609650348785969 Facebookhttps://www.facebook.com/BJReview/videos/466245403015094/ YouTubehttps://youtu.be/wce5rjaNIHM Weibohttps://weibo.com/1719349955/OlvWaBNUy Websitehttps://www.bjreview.com/Multimedia/Video/Wisdom_Without_Borders/202407/t20240701_800370249.html
Justice for Change pro bono recipients will be equipped with Relativity aiR for Review to further harness the power of AI for social good CHICAGO, Aug. 7, 2024 /PRNewswire/ -- Relativity, a global legal technology company, today announced ahead of ILTACON 2024 that qualifying pro bono recipients of the company's Justice for Change program will have free access to the generative AI-powered document review solution, Relativity aiR for Review, once generally available this September. Relativity "Adding generative AI to the Justice for Change offerings is part of our commitment to provide the best technology and support for organizations working toward closing the gap in access to justice," said Phil Saunders, CEO of Relativity. "Generative AI, when applied thoughtfully and responsibly, has immense potential to advance equity and make a meaningful impact. For often under-resourced pro bono teams, the valuable time saved with our technology enables them to take on more matters and ultimately help more people." Increasing Access to Justice with Generative AI Justice for Change pro bono recipients supported by a current RelativityOne partner or provider will be able to request access to use aiR for Review free of cost, enabling faster, more accurate, and insightful document review. Powered by generative AI, the solution provides detailed rationale and citations alongside predictions to help teams fully understand their data and results. "Since we began collaborating with a nonprofit legal organization through Relativity's Justice for Change program in 2022, Cimplifi has been able to host nearly 3 TB of data, encompassing documents, media, and testimony that all play a crucial role in shaping civil and criminal precedent. We are thrilled to learn that Relativity aiR for Review will be offered as part of the Justice for Change program, further enhancing our capacity to support this essential work," said Kristen Floyd, Associate Director, Strategic Engagements and Chairperson of the Diversity, Equity and Inclusion Committee at Cimplifi. "Access to generative AI-based technology will be a game-changer for Justice for Change participants, enhancing equity and accessibility. This work is vital to protecting our civil liberties and underscores the importance of accessible, efficient and reliable data solutions in the pursuit of justice." Through the Justice for Change program, Relativity aims to increase access to justice and empower pro bono recipients to tackle social and racial justice issues by using RelativityOne to make sense of data. Justice for Change pro bono recipients will not only have access to cutting-edge AI legal technology, but also to dedicated training, support, and community resources from Relativity and their ecosystem of partners. Currently, Justice for Change supports over 150 active matters, with 50 organizations leveraging Relativity on justice-oriented cases and projects and over 4 million documents reviewed through Relativity. Additionally, qualifying Justice for Change recipients will have free access to forthcoming Relativity aiR products and Translate in RelativityOne which leverages generative AI to streamline multi-lingual reviews. These products will enable Justice for Change hosting partners to handle complex and diverse data sets, and ultimately expedite and simplify the path to uncovering the truth. Celebrating One Year of Transformative Contract Review Relativity continues to support reviewers in making informed decisions faster. Since its launch at ILTACON last year, Relativity Contracts has enabled customers to do more in their contract review processes by transforming complex agreements into actionable, structured data that reveal better insights and drive faster decisions. Recently, Relativity Contracts Optical Character Recognition (OCR) capabilities were updated to support 10 new languages in addition to English. Now, the solution can recognize key terms and clauses in German, Portuguese, Chinese, Japanese, Korean, French, Italian, Spanish, Arabic and Dutch. Later this year, Relativity plans to release a Contracts Essential Fields model powered by aiR to automatically populate over 10 fields including parties, several key date fields, and more. Relativity at ILTACON 2024ILTACON 2024 will take place August 11-15 in Nashville, TN. The conference convenes industry experts and the legal community for peer-driven programs, educational content and face-to-face networking. Thought leaders from Relativity will participate in several sessions and discuss a range of topics including opportunities and challenges associated with AI, managing IT contracts, maintaining ethical standards in the face of rapid technological advancement, data privacy, the importance of metrics for corporate legal departments and prompt engineering. View the full agenda here. Attendees are encouraged to visit Relativity's booth #313 to learn more about the recent OpenAI ChatGPT Enterprise Compliance API integration, and see a video demo of the new RelativityOne and Cellebrite Remote Mobile Collection and Conversation integration. Those interested in setting up a one-on-one meeting at ILTACON 2024 can contact sales@relativity.com. Relativity is a proud business partner of the International Legal Technology Association (ILTA) and earlier this year was a recipient of two ILTA 2024 Distinguished Peer Awards. David Horrigan, Discovery Counsel and Legal Education Director at Relativity, was honored with the Lifetime Achievement Award, which recognizes a career exemplifying a record of contributions to the legal sector. Relativity's former Brand Content Program Manager, Blair Cohen, was named an honoree on ILTA's Young Professionals to Watch List for her achievements at Relativity and throughout the legal technology industry. About RelativityRelativity makes software to help users organize data, discover the truth and act on it. Its SaaS product, RelativityOne, manages large volumes of data and quickly identifies key issues during litigation and internal investigations. Relativity has more than 300,000 users in approximately 40 countries serving thousands of organizations globally primarily in legal, financial services and government sectors, including the U.S. Department of Justice and 198 of the Am Law 200. Please contact Relativity at sales@relativity.com or visit www.relativity.com for more information. CONTACT: PR@relativity.com
A12 藝術空間
請先登入後才能發佈新聞。
還不是會員嗎？立即 加入台灣產經新聞網會員 ，使用免費新聞發佈服務。 （服務項目） （投稿規範）
